The global Rolling Circle Amplification market size was valued at US$ 1034 million in 2024 and is forecast to a readjusted size of USD 1995 million by 2031 with a CAGR of 10.0% during review period.
Rolling circle amplification (RCA) is an isothermal enzymatic process that uses a circular DNA template and special DNA or RNA polymerases to amplify a short DNA or RNA primer to form a long single stranded DNA or RNA. The RCA product is a concatemer composed of tens to hundreds of tandem repeats that complement the circular template. The DNA amplification technique"s power, simplicity, and versatility have made it an appealing tool for biomedical research and nanobiotechnology. RCA has traditionally been used to create sensitive diagnostic methods for a wide range of targets such as nucleic acids (DNA, RNA), small molecules, proteins, and cells. RCA has also received a great deal of attention in the fields of nanotechnology and nanobiotechnology.
Immuno-RCA uses antibodies conjugated to oligonucleotides to detect individual proteins. A circular DNA template can be hybridized to it and then amplified by the enzyme phi29 polymerase using antibody-conjugated oligonucleotides as primers. This will result in the formation of RCP covalently linked to the antibody. Two antibodies are conjugated to two different oligonucleotides in PLA (proximity probes). Proximity probes are assumed to bind to their very close targets. In this case, they will serve as hybridization/ligation templates for two other oligonucleotides, resulting in a circular DNA template that can be amplified using one of the proximity probes as an RCA primer. The increasing application of rolling circle amplification has resulted in high growth of the rolling circle amplification market.
This report is a detailed and comprehensive analysis for global Rolling Circle Amplification market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2025, are provided.
Key Features:
Global Rolling Circle Amplification market size and forecasts, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031
Global Rolling Circle Amplification market size and forecasts by region and country, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031
Global Rolling Circle Amplification market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (K Units), and average selling prices (US$/Unit), 2020-2031
Global Rolling Circle Amplification market shares of main players, shipments in revenue ($ Million), sales quantity (K Units), and ASP (US$/Unit), 2020-2025
The Primary Objectives in This Report Are:
To determine the size of the total market opportunity of global and key countries
To assess the growth potential for Rolling Circle Amplification
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace
This report profiles key players in the global Rolling Circle Amplification market based on the following parameters - company overview, sales quantity, revenue, price, gross margin, product portfolio, geographical presence, and key developments. Key companies covered as a part of this study include Thermo Fisher Scientific Inc, Abbott, QIAGEN, Agilent Technologies Inc, Bayer AG, BD, F. Hoffmann-La Roche Ltd, µþ±õ°¿²Ñɸé±õ·¡±«³Ý, Bio-Rad Laboratories Inc, Takara Bio, Inc, etc.
This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals.
Market Segmentation
Rolling Circle Amplification market is split by Type and by Application. For the period 2020-2031, the growth among segments provides accurate calculations and forecasts for consumption value by Type, and by Application in terms of volume and value. This analysis can help you expand your business by targeting qualified niche markets.
Market segment by Type
Enzyme Assisted RCA Biosensor
Aunp RCA Biosensor
Aptamer Biosensors
Small Molecule Biosensors
Transcription Factor Biosensors
Mirna Biosensors
Protein Biosensors
Market segment by Application
Disease Diagnosis
Biosensing
Drug Discovery
Nanotechnology
Other
Major players covered
Thermo Fisher Scientific Inc
Abbott
QIAGEN
Agilent Technologies Inc
Bayer AG
BD
F. Hoffmann-La Roche Ltd
µþ±õ°¿²Ñɸé±õ·¡±«³Ý
Bio-Rad Laboratories Inc
Takara Bio, Inc
Market segment by region, regional analysis covers
North America (United States, Canada, and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
The content of the study subjects, includes a total of 15 chapters:
Chapter 1, to describe Rolling Circle Amplification product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of Rolling Circle Amplification, with price, sales quantity, revenue, and global market share of Rolling Circle Amplification from 2020 to 2025.
Chapter 3, the Rolling Circle Amplification competitive situation, sales quantity, revenue, and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the Rolling Circle Amplification breakdown data are shown at the regional level, to show the sales quantity, consumption value, and growth by regions, from 2020 to 2031.
Chapter 5 and 6, to segment the sales by Type and by Application, with sales market share and growth rate by Type, by Application, from 2020 to 2031.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value, and market share for key countries in the world, from 2020 to 2025.and Rolling Circle Amplification market forecast, by regions, by Type, and by Application, with sales and revenue, from 2026 to 2031.
Chapter 12, market dynamics, drivers, restraints, trends, and Porters Five Forces analysis.
Chapter 13, the key raw materials and key suppliers, and industry chain of Rolling Circle Amplification.
Chapter 14 and 15, to describe Rolling Circle Amplification sales channel, distributors, customers, research findings and conclusion.
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1 Market Overview
1.1 Product Overview and Scope
1.2 Market Estimation Caveats and Base Year
1.3 Market Analysis by Type
1.3.1 Overview: Global Rolling Circle Amplification Consumption Value by Type: 2020 Versus 2024 Versus 2031
1.3.2 Enzyme Assisted RCA Biosensor
1.3.3 Aunp RCA Biosensor
1.3.4 Aptamer Biosensors
1.3.5 Small Molecule Biosensors
1.3.6 Transcription Factor Biosensors
1.3.7 Mirna Biosensors
1.3.8 Protein Biosensors
1.4 Market Analysis by Application
1.4.1 Overview: Global Rolling Circle Amplification Consumption Value by Application: 2020 Versus 2024 Versus 2031
1.4.2 Disease Diagnosis
1.4.3 Biosensing
1.4.4 Drug Discovery
1.4.5 Nanotechnology
1.4.6 Other
1.5 Global Rolling Circle Amplification Market Size & Forecast
1.5.1 Global Rolling Circle Amplification Consumption Value (2020 & 2024 & 2031)
1.5.2 Global Rolling Circle Amplification Sales Quantity (2020-2031)
1.5.3 Global Rolling Circle Amplification Average Price (2020-2031)
2 Manufacturers Profiles
2.1 Thermo Fisher Scientific Inc
2.1.1 Thermo Fisher Scientific Inc Details
2.1.2 Thermo Fisher Scientific Inc Major Business
2.1.3 Thermo Fisher Scientific Inc Rolling Circle Amplification Product and Services
2.1.4 Thermo Fisher Scientific Inc Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.1.5 Thermo Fisher Scientific Inc Recent Developments/Updates
2.2 Abbott
2.2.1 Abbott Details
2.2.2 Abbott Major Business
2.2.3 Abbott Rolling Circle Amplification Product and Services
2.2.4 Abbott Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.2.5 Abbott Recent Developments/Updates
2.3 QIAGEN
2.3.1 QIAGEN Details
2.3.2 QIAGEN Major Business
2.3.3 QIAGEN Rolling Circle Amplification Product and Services
2.3.4 QIAGEN Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.3.5 QIAGEN Recent Developments/Updates
2.4 Agilent Technologies Inc
2.4.1 Agilent Technologies Inc Details
2.4.2 Agilent Technologies Inc Major Business
2.4.3 Agilent Technologies Inc Rolling Circle Amplification Product and Services
2.4.4 Agilent Technologies Inc Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.4.5 Agilent Technologies Inc Recent Developments/Updates
2.5 Bayer AG
2.5.1 Bayer AG Details
2.5.2 Bayer AG Major Business
2.5.3 Bayer AG Rolling Circle Amplification Product and Services
2.5.4 Bayer AG Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.5.5 Bayer AG Recent Developments/Updates
2.6 BD
2.6.1 BD Details
2.6.2 BD Major Business
2.6.3 BD Rolling Circle Amplification Product and Services
2.6.4 BD Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.6.5 BD Recent Developments/Updates
2.7 F. Hoffmann-La Roche Ltd
2.7.1 F. Hoffmann-La Roche Ltd Details
2.7.2 F. Hoffmann-La Roche Ltd Major Business
2.7.3 F. Hoffmann-La Roche Ltd Rolling Circle Amplification Product and Services
2.7.4 F. Hoffmann-La Roche Ltd Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.7.5 F. Hoffmann-La Roche Ltd Recent Developments/Updates
2.8 µþ±õ°¿²Ñɸé±õ·¡±«³Ý
2.8.1 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Details
2.8.2 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Major Business
2.8.3 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Rolling Circle Amplification Product and Services
2.8.4 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.8.5 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Recent Developments/Updates
2.9 Bio-Rad Laboratories Inc
2.9.1 Bio-Rad Laboratories Inc Details
2.9.2 Bio-Rad Laboratories Inc Major Business
2.9.3 Bio-Rad Laboratories Inc Rolling Circle Amplification Product and Services
2.9.4 Bio-Rad Laboratories Inc Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.9.5 Bio-Rad Laboratories Inc Recent Developments/Updates
2.10 Takara Bio, Inc
2.10.1 Takara Bio, Inc Details
2.10.2 Takara Bio, Inc Major Business
2.10.3 Takara Bio, Inc Rolling Circle Amplification Product and Services
2.10.4 Takara Bio, Inc Rolling Circle Amplification Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2020-2025)
2.10.5 Takara Bio, Inc Recent Developments/Updates
3 Competitive Environment: Rolling Circle Amplification by Manufacturer
3.1 Global Rolling Circle Amplification Sales Quantity by Manufacturer (2020-2025)
3.2 Global Rolling Circle Amplification Revenue by Manufacturer (2020-2025)
3.3 Global Rolling Circle Amplification Average Price by Manufacturer (2020-2025)
3.4 Market Share Analysis (2024)
3.4.1 Producer Shipments of Rolling Circle Amplification by Manufacturer Revenue ($MM) and Market Share (%): 2024
3.4.2 Top 3 Rolling Circle Amplification Manufacturer Market Share in 2024
3.4.3 Top 6 Rolling Circle Amplification Manufacturer Market Share in 2024
3.5 Rolling Circle Amplification Market: Overall Company Footprint Analysis
3.5.1 Rolling Circle Amplification Market: Region Footprint
3.5.2 Rolling Circle Amplification Market: Company Product Type Footprint
3.5.3 Rolling Circle Amplification Market: Company Product Application Footprint
3.6 New Market Entrants and Barriers to Market Entry
3.7 Mergers, Acquisition, Agreements, and Collaborations
4 Consumption Analysis by Region
4.1 Global Rolling Circle Amplification Market Size by Region
4.1.1 Global Rolling Circle Amplification Sales Quantity by Region (2020-2031)
4.1.2 Global Rolling Circle Amplification Consumption Value by Region (2020-2031)
4.1.3 Global Rolling Circle Amplification Average Price by Region (2020-2031)
4.2 North America Rolling Circle Amplification Consumption Value (2020-2031)
4.3 Europe Rolling Circle Amplification Consumption Value (2020-2031)
4.4 Asia-Pacific Rolling Circle Amplification Consumption Value (2020-2031)
4.5 South America Rolling Circle Amplification Consumption Value (2020-2031)
4.6 Middle East & Africa Rolling Circle Amplification Consumption Value (2020-2031)
5 Market Segment by Type
5.1 Global Rolling Circle Amplification Sales Quantity by Type (2020-2031)
5.2 Global Rolling Circle Amplification Consumption Value by Type (2020-2031)
5.3 Global Rolling Circle Amplification Average Price by Type (2020-2031)
6 Market Segment by Application
6.1 Global Rolling Circle Amplification Sales Quantity by Application (2020-2031)
6.2 Global Rolling Circle Amplification Consumption Value by Application (2020-2031)
6.3 Global Rolling Circle Amplification Average Price by Application (2020-2031)
7 North America
7.1 North America Rolling Circle Amplification Sales Quantity by Type (2020-2031)
7.2 North America Rolling Circle Amplification Sales Quantity by Application (2020-2031)
7.3 North America Rolling Circle Amplification Market Size by Country
7.3.1 North America Rolling Circle Amplification Sales Quantity by Country (2020-2031)
7.3.2 North America Rolling Circle Amplification Consumption Value by Country (2020-2031)
7.3.3 United States Market Size and Forecast (2020-2031)
7.3.4 Canada Market Size and Forecast (2020-2031)
7.3.5 Mexico Market Size and Forecast (2020-2031)
8 Europe
8.1 Europe Rolling Circle Amplification Sales Quantity by Type (2020-2031)
8.2 Europe Rolling Circle Amplification Sales Quantity by Application (2020-2031)
8.3 Europe Rolling Circle Amplification Market Size by Country
8.3.1 Europe Rolling Circle Amplification Sales Quantity by Country (2020-2031)
8.3.2 Europe Rolling Circle Amplification Consumption Value by Country (2020-2031)
8.3.3 Germany Market Size and Forecast (2020-2031)
8.3.4 France Market Size and Forecast (2020-2031)
8.3.5 United Kingdom Market Size and Forecast (2020-2031)
8.3.6 Russia Market Size and Forecast (2020-2031)
8.3.7 Italy Market Size and Forecast (2020-2031)
9 Asia-Pacific
9.1 Asia-Pacific Rolling Circle Amplification Sales Quantity by Type (2020-2031)
9.2 Asia-Pacific Rolling Circle Amplification Sales Quantity by Application (2020-2031)
9.3 Asia-Pacific Rolling Circle Amplification Market Size by Region
9.3.1 Asia-Pacific Rolling Circle Amplification Sales Quantity by Region (2020-2031)
9.3.2 Asia-Pacific Rolling Circle Amplification Consumption Value by Region (2020-2031)
9.3.3 China Market Size and Forecast (2020-2031)
9.3.4 Japan Market Size and Forecast (2020-2031)
9.3.5 South Korea Market Size and Forecast (2020-2031)
9.3.6 India Market Size and Forecast (2020-2031)
9.3.7 Southeast Asia Market Size and Forecast (2020-2031)
9.3.8 Australia Market Size and Forecast (2020-2031)
10 South America
10.1 South America Rolling Circle Amplification Sales Quantity by Type (2020-2031)
10.2 South America Rolling Circle Amplification Sales Quantity by Application (2020-2031)
10.3 South America Rolling Circle Amplification Market Size by Country
10.3.1 South America Rolling Circle Amplification Sales Quantity by Country (2020-2031)
10.3.2 South America Rolling Circle Amplification Consumption Value by Country (2020-2031)
10.3.3 Brazil Market Size and Forecast (2020-2031)
10.3.4 Argentina Market Size and Forecast (2020-2031)
11 Middle East & Africa
11.1 Middle East & Africa Rolling Circle Amplification Sales Quantity by Type (2020-2031)
11.2 Middle East & Africa Rolling Circle Amplification Sales Quantity by Application (2020-2031)
11.3 Middle East & Africa Rolling Circle Amplification Market Size by Country
11.3.1 Middle East & Africa Rolling Circle Amplification Sales Quantity by Country (2020-2031)
11.3.2 Middle East & Africa Rolling Circle Amplification Consumption Value by Country (2020-2031)
11.3.3 Turkey Market Size and Forecast (2020-2031)
11.3.4 Egypt Market Size and Forecast (2020-2031)
11.3.5 Saudi Arabia Market Size and Forecast (2020-2031)
11.3.6 South Africa Market Size and Forecast (2020-2031)
12 Market Dynamics
12.1 Rolling Circle Amplification Market Drivers
12.2 Rolling Circle Amplification Market Restraints
12.3 Rolling Circle Amplification Trends Analysis
12.4 Porters Five Forces Analysis
12.4.1 Threat of New Entrants
12.4.2 Bargaining Power of Suppliers
12.4.3 Bargaining Power of Buyers
12.4.4 Threat of Substitutes
12.4.5 Competitive Rivalry
13 Raw Material and Industry Chain
13.1 Raw Material of Rolling Circle Amplification and Key Manufacturers
13.2 Manufacturing Costs Percentage of Rolling Circle Amplification
13.3 Rolling Circle Amplification Production Process
13.4 Industry Value Chain Analysis
14 Shipments by Distribution Channel
14.1 Sales Channel
14.1.1 Direct to End-User
14.1.2 Distributors
14.2 Rolling Circle Amplification Typical Distributors
14.3 Rolling Circle Amplification Typical Customers
15 Research Findings and Conclusion
16 Appendix
16.1 Methodology
16.2 Research Process and Data Source
16.3 Disclaimer
Thermo Fisher Scientific Inc
Abbott
QIAGEN
Agilent Technologies Inc
Bayer AG
BD
F. Hoffmann-La Roche Ltd
µþ±õ°¿²Ñɸé±õ·¡±«³Ý
Bio-Rad Laboratories Inc
Takara Bio, Inc
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*If Applicable.
