
The global Enzyme Replacement Therapy market size is predicted to grow from US$ 16900 million in 2025 to US$ 38130 million in 2031; it is expected to grow at a CAGR of 14.5% from 2025 to 2031.
Enzyme replacement therapy (ERT) is a medical treatment which replaces an enzyme that is deficient or absent in the body. Usually, this is done by giving the patient an intravenous (IV) infusion of a solution containing the enzyme.
Global Enzyme Replacement Therapy key players include Johnson & Johnson, Allergan, AbbVie, etc. Global top three manufacturers hold a share about 95%.
North America is the largest market, with a share about 70%, followed by Europe, and Asia-Pacific, both have a share over 25 percent.
In terms of product, Oral Agents is the largest segment, with a share nearly 95%. And in terms of application, the largest application is MPS Disease, followed by Gastrointestinal Diseases, Gaucher Disease, Fabry Disease, etc.
The “Enzyme Replacement Therapy Industry Forecast” looks at past sales and reviews total world Enzyme Replacement Therapy sales in 2024, providing a comprehensive analysis by region and market sector of projected Enzyme Replacement Therapy sales for 2025 through 2031. With Enzyme Replacement Therapy sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Enzyme Replacement Therapy industry.
This Insight Report provides a comprehensive analysis of the global Enzyme Replacement Therapy landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on Enzyme Replacement Therapy portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Enzyme Replacement Therapy market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Enzyme Replacement Therapy and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Enzyme Replacement Therapy.
This report presents a comprehensive overview, market shares, and growth opportunities of Enzyme Replacement Therapy market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
Injectable Agents
Oral Agents
Segmentation by Application:
Gaucher Disease
Fabry Disease
MPS Disease
Gastrointestinal Disease
Others
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Sanofi
Takeda
BioMarin
AbbVie
Alexion
Allergan
Horizon Pharma
Johnson & Johnson
Actelion
Recordati Rare Diseases
Pfizer
Digestive Care
Leadiant Biosciences
Key Questions Addressed in this Report
What is the 10-year outlook for the global Enzyme Replacement Therapy market?
What factors are driving Enzyme Replacement Therapy market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do Enzyme Replacement Therapy market opportunities vary by end market size?
How does Enzyme Replacement Therapy break out by Type, by Application?
Please Note - This is an on demand report and will be delivered in 2 business days (48 hours) post payment.
1 Scope of the Report
1.1 Market Introduction
1.2 Years Considered
1.3 Research Objectives
1.4 Market Research Methodology
1.5 Research Process and Data Source
1.6 Economic Indicators
1.7 Currency Considered
1.8 Market Estimation Caveats
2 Executive Summary
2.1 World Market Overview
2.1.1 Global Enzyme Replacement Therapy Annual Sales 2020-2031
2.1.2 World Current & Future Analysis for Enzyme Replacement Therapy by Geographic Region, 2020, 2024 & 2031
2.1.3 World Current & Future Analysis for Enzyme Replacement Therapy by Country/Region, 2020, 2024 & 2031
2.2 Enzyme Replacement Therapy Segment by Type
2.2.1 Injectable Agents
2.2.2 Oral Agents
2.3 Enzyme Replacement Therapy Sales by Type
2.3.1 Global Enzyme Replacement Therapy Sales Market Share by Type (2020-2025)
2.3.2 Global Enzyme Replacement Therapy Revenue and Market Share by Type (2020-2025)
2.3.3 Global Enzyme Replacement Therapy Sale Price by Type (2020-2025)
2.4 Enzyme Replacement Therapy Segment by Application
2.4.1 Gaucher Disease
2.4.2 Fabry Disease
2.4.3 MPS Disease
2.4.4 Gastrointestinal Disease
2.4.5 Others
2.5 Enzyme Replacement Therapy Sales by Application
2.5.1 Global Enzyme Replacement Therapy Sale Market Share by Application (2020-2025)
2.5.2 Global Enzyme Replacement Therapy Revenue and Market Share by Application (2020-2025)
2.5.3 Global Enzyme Replacement Therapy Sale Price by Application (2020-2025)
3 Global by Company
3.1 Global Enzyme Replacement Therapy Breakdown Data by Company
3.1.1 Global Enzyme Replacement Therapy Annual Sales by Company (2020-2025)
3.1.2 Global Enzyme Replacement Therapy Sales Market Share by Company (2020-2025)
3.2 Global Enzyme Replacement Therapy Annual Revenue by Company (2020-2025)
3.2.1 Global Enzyme Replacement Therapy Revenue by Company (2020-2025)
3.2.2 Global Enzyme Replacement Therapy Revenue Market Share by Company (2020-2025)
3.3 Global Enzyme Replacement Therapy Sale Price by Company
3.4 Key Manufacturers Enzyme Replacement Therapy Producing Area Distribution, Sales Area, Product Type
3.4.1 Key Manufacturers Enzyme Replacement Therapy Product Location Distribution
3.4.2 Players Enzyme Replacement Therapy Products Offered
3.5 Market Concentration Rate Analysis
3.5.1 Competition Landscape Analysis
3.5.2 Concentration Ratio (CR3, CR5 and CR10) & (2023-2025)
3.6 New Products and Potential Entrants
3.7 Market M&A Activity & Strategy
4 World Historic Review for Enzyme Replacement Therapy by Geographic Region
4.1 World Historic Enzyme Replacement Therapy Market Size by Geographic Region (2020-2025)
4.1.1 Global Enzyme Replacement Therapy Annual Sales by Geographic Region (2020-2025)
4.1.2 Global Enzyme Replacement Therapy Annual Revenue by Geographic Region (2020-2025)
4.2 World Historic Enzyme Replacement Therapy Market Size by Country/Region (2020-2025)
4.2.1 Global Enzyme Replacement Therapy Annual Sales by Country/Region (2020-2025)
4.2.2 Global Enzyme Replacement Therapy Annual Revenue by Country/Region (2020-2025)
4.3 Americas Enzyme Replacement Therapy Sales Growth
4.4 APAC Enzyme Replacement Therapy Sales Growth
4.5 Europe Enzyme Replacement Therapy Sales Growth
4.6 Middle East & Africa Enzyme Replacement Therapy Sales Growth
5 Americas
5.1 Americas Enzyme Replacement Therapy Sales by Country
5.1.1 Americas Enzyme Replacement Therapy Sales by Country (2020-2025)
5.1.2 Americas Enzyme Replacement Therapy Revenue by Country (2020-2025)
5.2 Americas Enzyme Replacement Therapy Sales by Type (2020-2025)
5.3 Americas Enzyme Replacement Therapy Sales by Application (2020-2025)
5.4 United States
5.5 Canada
5.6 Mexico
5.7 Brazil
6 APAC
6.1 APAC Enzyme Replacement Therapy Sales by Region
6.1.1 APAC Enzyme Replacement Therapy Sales by Region (2020-2025)
6.1.2 APAC Enzyme Replacement Therapy Revenue by Region (2020-2025)
6.2 APAC Enzyme Replacement Therapy Sales by Type (2020-2025)
6.3 APAC Enzyme Replacement Therapy Sales by Application (2020-2025)
6.4 China
6.5 Japan
6.6 South Korea
6.7 Southeast Asia
6.8 India
6.9 Australia
6.10 China Taiwan
7 Europe
7.1 Europe Enzyme Replacement Therapy by Country
7.1.1 Europe Enzyme Replacement Therapy Sales by Country (2020-2025)
7.1.2 Europe Enzyme Replacement Therapy Revenue by Country (2020-2025)
7.2 Europe Enzyme Replacement Therapy Sales by Type (2020-2025)
7.3 Europe Enzyme Replacement Therapy Sales by Application (2020-2025)
7.4 Germany
7.5 France
7.6 UK
7.7 Italy
7.8 Russia
8 Middle East & Africa
8.1 Middle East & Africa Enzyme Replacement Therapy by Country
8.1.1 Middle East & Africa Enzyme Replacement Therapy Sales by Country (2020-2025)
8.1.2 Middle East & Africa Enzyme Replacement Therapy Revenue by Country (2020-2025)
8.2 Middle East & Africa Enzyme Replacement Therapy Sales by Type (2020-2025)
8.3 Middle East & Africa Enzyme Replacement Therapy Sales by Application (2020-2025)
8.4 Egypt
8.5 South Africa
8.6 Israel
8.7 Turkey
8.8 GCC Countries
9 Market Drivers, Challenges and Trends
9.1 Market Drivers & Growth Opportunities
9.2 Market Challenges & Risks
9.3 Industry Trends
10 Manufacturing Cost Structure Analysis
10.1 Raw Material and Suppliers
10.2 Manufacturing Cost Structure Analysis of Enzyme Replacement Therapy
10.3 Manufacturing Process Analysis of Enzyme Replacement Therapy
10.4 Industry Chain Structure of Enzyme Replacement Therapy
11 Marketing, Distributors and Customer
11.1 Sales Channel
11.1.1 Direct Channels
11.1.2 Indirect Channels
11.2 Enzyme Replacement Therapy Distributors
11.3 Enzyme Replacement Therapy Customer
12 World Forecast Review for Enzyme Replacement Therapy by Geographic Region
12.1 Global Enzyme Replacement Therapy Market Size Forecast by Region
12.1.1 Global Enzyme Replacement Therapy Forecast by Region (2026-2031)
12.1.2 Global Enzyme Replacement Therapy Annual Revenue Forecast by Region (2026-2031)
12.2 Americas Forecast by Country (2026-2031)
12.3 APAC Forecast by Region (2026-2031)
12.4 Europe Forecast by Country (2026-2031)
12.5 Middle East & Africa Forecast by Country (2026-2031)
12.6 Global Enzyme Replacement Therapy Forecast by Type (2026-2031)
12.7 Global Enzyme Replacement Therapy Forecast by Application (2026-2031)
13 Key Players Analysis
13.1 Sanofi
13.1.1 Sanofi Company Information
13.1.2 Sanofi Enzyme Replacement Therapy Product Portfolios and Specifications
13.1.3 Sanofi Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.1.4 Sanofi Main Business Overview
13.1.5 Sanofi Latest Developments
13.2 Takeda
13.2.1 Takeda Company Information
13.2.2 Takeda Enzyme Replacement Therapy Product Portfolios and Specifications
13.2.3 Takeda Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.2.4 Takeda Main Business Overview
13.2.5 Takeda Latest Developments
13.3 BioMarin
13.3.1 BioMarin Company Information
13.3.2 BioMarin Enzyme Replacement Therapy Product Portfolios and Specifications
13.3.3 BioMarin Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.3.4 BioMarin Main Business Overview
13.3.5 BioMarin Latest Developments
13.4 AbbVie
13.4.1 AbbVie Company Information
13.4.2 AbbVie Enzyme Replacement Therapy Product Portfolios and Specifications
13.4.3 AbbVie Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.4.4 AbbVie Main Business Overview
13.4.5 AbbVie Latest Developments
13.5 Alexion
13.5.1 Alexion Company Information
13.5.2 Alexion Enzyme Replacement Therapy Product Portfolios and Specifications
13.5.3 Alexion Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.5.4 Alexion Main Business Overview
13.5.5 Alexion Latest Developments
13.6 Allergan
13.6.1 Allergan Company Information
13.6.2 Allergan Enzyme Replacement Therapy Product Portfolios and Specifications
13.6.3 Allergan Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.6.4 Allergan Main Business Overview
13.6.5 Allergan Latest Developments
13.7 Horizon Pharma
13.7.1 Horizon Pharma Company Information
13.7.2 Horizon Pharma Enzyme Replacement Therapy Product Portfolios and Specifications
13.7.3 Horizon Pharma Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.7.4 Horizon Pharma Main Business Overview
13.7.5 Horizon Pharma Latest Developments
13.8 Johnson & Johnson
13.8.1 Johnson & Johnson Company Information
13.8.2 Johnson & Johnson Enzyme Replacement Therapy Product Portfolios and Specifications
13.8.3 Johnson & Johnson Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.8.4 Johnson & Johnson Main Business Overview
13.8.5 Johnson & Johnson Latest Developments
13.9 Actelion
13.9.1 Actelion Company Information
13.9.2 Actelion Enzyme Replacement Therapy Product Portfolios and Specifications
13.9.3 Actelion Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.9.4 Actelion Main Business Overview
13.9.5 Actelion Latest Developments
13.10 Recordati Rare Diseases
13.10.1 Recordati Rare Diseases Company Information
13.10.2 Recordati Rare Diseases Enzyme Replacement Therapy Product Portfolios and Specifications
13.10.3 Recordati Rare Diseases Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.10.4 Recordati Rare Diseases Main Business Overview
13.10.5 Recordati Rare Diseases Latest Developments
13.11 Pfizer
13.11.1 Pfizer Company Information
13.11.2 Pfizer Enzyme Replacement Therapy Product Portfolios and Specifications
13.11.3 Pfizer Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.11.4 Pfizer Main Business Overview
13.11.5 Pfizer Latest Developments
13.12 Digestive Care
13.12.1 Digestive Care Company Information
13.12.2 Digestive Care Enzyme Replacement Therapy Product Portfolios and Specifications
13.12.3 Digestive Care Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.12.4 Digestive Care Main Business Overview
13.12.5 Digestive Care Latest Developments
13.13 Leadiant Biosciences
13.13.1 Leadiant Biosciences Company Information
13.13.2 Leadiant Biosciences Enzyme Replacement Therapy Product Portfolios and Specifications
13.13.3 Leadiant Biosciences Enzyme Replacement Therapy Sales, Revenue, Price and Gross Margin (2020-2025)
13.13.4 Leadiant Biosciences Main Business Overview
13.13.5 Leadiant Biosciences Latest Developments
14 Research Findings and Conclusion
*If Applicable.
