The global High-performance Liquid Chromatography (HPLC) market size is predicted to grow from US$ 3555 million in 2025 to US$ 4351 million in 2031; it is expected to grow at a CAGR of 3.4% from 2025 to 2031.
The impact of the latest U.S. tariff measures and the corresponding policy responses from countries worldwide on market competitiveness, regional economic performance, and supply chain configurations will be comprehensively evaluated in this report.
High-performance liquid chromatography (HPLC) is a technique in analytic chemistry used to separate the components in a mixture, to identify each component, and to quantify each component. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.
Market Development Opportunities & Main Driving Factors
Driven by the growing need for high-precision and high-throughput analytical methods in pharmaceuticals, biotechnology, food safety, and environmental monitoring, the HPLC market is experiencing steady expansion. Particularly in drug discovery, biologics analysis, and metabolomics research, HPLC has become a core analytical tool. Additionally, stricter regulatory standards for pharmaceuticals, food products, and environmental safety are prompting greater investment in advanced analytical instruments, thereby boosting market growth.
Market Challenges, Risks, & Restraints
Despite its promising outlook, the HPLC sector faces challenges such as high equipment costs, complex operation and maintenance requirements, and a shortage of skilled professionals—especially in emerging markets. Moreover, the risk of technological substitution must be considered, with newer techniques like Ultra Performance Liquid Chromatography (UPLC) potentially replacing conventional HPLC systems in some applications, reshaping the market landscape.
Downstream Demand Trends
Downstream demand is shifting from traditional pharmaceutical testing to more diversified applications, including biopharmaceuticals, food additives, cosmetic ingredients, and environmental toxins. With the rise of precision medicine and personalized therapies, clinical sample analysis and pharmacokinetic studies are driving continued demand for HPLC systems with higher sensitivity and advanced data processing capabilities.
EU is the largest High-performance Liquid Chromatography (HPLC) market with about 34% market share. US is follower, accounting for about 34% market share. The key players are Agilent, Waters, Shimadzu, Thermo Fisher, PerkinElmer, Hitachi, Jasco, Knauer, Bekman, YoungLin, GBC, Gilson etc. Top 3 companies occupied about 66% market share.
The “High-performance Liquid Chromatography (HPLC) Industry Forecast” looks at past sales and reviews total world High-performance Liquid Chromatography (HPLC) sales in 2024, providing a comprehensive analysis by region and market sector of projected High-performance Liquid Chromatography (HPLC) sales for 2025 through 2031. With High-performance Liquid Chromatography (HPLC) sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world High-performance Liquid Chromatography (HPLC) industry.
This Insight Report provides a comprehensive analysis of the global High-performance Liquid Chromatography (HPLC) landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyzes the strategies of leading global companies with a focus on High-performance Liquid Chromatography (HPLC) portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global High-performance Liquid Chromatography (HPLC) market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for High-performance Liquid Chromatography (HPLC) and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global High-performance Liquid Chromatography (HPLC).
This report presents a comprehensive overview, market shares, and growth opportunities of High-performance Liquid Chromatography (HPLC) market by product type, application, key manufacturers and key regions and countries.
Segmentation by Type:
UVS
FD
RID
ED
CD
Segmentation by Application:
Pharmacy
Biotechnology
CROs
Academia
Chemicals
Others
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analysing the company's coverage, product portfolio, its market penetration.
Agilent
Waters
Shimadzu
Thermo Fisher
PerkinElmer
Hitachi
Jasco
Knauer
Bekman
YoungLin
GBC
Gilson
Key Questions Addressed in this Report
What is the 10-year outlook for the global High-performance Liquid Chromatography (HPLC) market?
What factors are driving High-performance Liquid Chromatography (HPLC) market growth, globally and by region?
Which technologies are poised for the fastest growth by market and region?
How do High-performance Liquid Chromatography (HPLC) market opportunities vary by end market size?
How does High-performance Liquid Chromatography (HPLC) break out by Type, by Application?
Please Note - This is an on demand report and will be delivered in 2 business days (48 hours) post payment.
1 Scope of the Report
1.1 Market Introduction
1.2 Years Considered
1.3 Research Objectives
1.4 Market Research Methodology
1.5 Research Process and Data Source
1.6 Economic Indicators
1.7 Currency Considered
1.8 Market Estimation Caveats
2 Executive Summary
2.1 World Market Overview
2.1.1 Global High-performance Liquid Chromatography (HPLC) Annual Sales 2020-2031
2.1.2 World Current & Future Analysis for High-performance Liquid Chromatography (HPLC) by Geographic Region, 2020, 2024 & 2031
2.1.3 World Current & Future Analysis for High-performance Liquid Chromatography (HPLC) by Country/Region, 2020, 2024 & 2031
2.2 High-performance Liquid Chromatography (HPLC) Segment by Type
2.2.1 UVS
2.2.2 FD
2.2.3 RID
2.2.4 ED
2.2.5 CD
2.3 High-performance Liquid Chromatography (HPLC) Sales by Type
2.3.1 Global High-performance Liquid Chromatography (HPLC) Sales Market Share by Type (2020-2025)
2.3.2 Global High-performance Liquid Chromatography (HPLC) Revenue and Market Share by Type (2020-2025)
2.3.3 Global High-performance Liquid Chromatography (HPLC) Sale Price by Type (2020-2025)
2.4 High-performance Liquid Chromatography (HPLC) Segment by Application
2.4.1 Pharmacy
2.4.2 Biotechnology
2.4.3 CROs
2.4.4 Academia
2.4.5 Chemicals
2.4.6 Others
2.5 High-performance Liquid Chromatography (HPLC) Sales by Application
2.5.1 Global High-performance Liquid Chromatography (HPLC) Sale Market Share by Application (2020-2025)
2.5.2 Global High-performance Liquid Chromatography (HPLC) Revenue and Market Share by Application (2020-2025)
2.5.3 Global High-performance Liquid Chromatography (HPLC) Sale Price by Application (2020-2025)
3 Global by Company
3.1 Global High-performance Liquid Chromatography (HPLC) Breakdown Data by Company
3.1.1 Global High-performance Liquid Chromatography (HPLC) Annual Sales by Company (2020-2025)
3.1.2 Global High-performance Liquid Chromatography (HPLC) Sales Market Share by Company (2020-2025)
3.2 Global High-performance Liquid Chromatography (HPLC) Annual Revenue by Company (2020-2025)
3.2.1 Global High-performance Liquid Chromatography (HPLC) Revenue by Company (2020-2025)
3.2.2 Global High-performance Liquid Chromatography (HPLC) Revenue Market Share by Company (2020-2025)
3.3 Global High-performance Liquid Chromatography (HPLC) Sale Price by Company
3.4 Key Manufacturers High-performance Liquid Chromatography (HPLC) Producing Area Distribution, Sales Area, Product Type
3.4.1 Key Manufacturers High-performance Liquid Chromatography (HPLC) Product Location Distribution
3.4.2 Players High-performance Liquid Chromatography (HPLC) Products Offered
3.5 Market Concentration Rate Analysis
3.5.1 Competition Landscape Analysis
3.5.2 Concentration Ratio (CR3, CR5 and CR10) & (2023-2025)
3.6 New Products and Potential Entrants
3.7 Market M&A Activity & Strategy
4 World Historic Review for High-performance Liquid Chromatography (HPLC) by Geographic Region
4.1 World Historic High-performance Liquid Chromatography (HPLC) Market Size by Geographic Region (2020-2025)
4.1.1 Global High-performance Liquid Chromatography (HPLC) Annual Sales by Geographic Region (2020-2025)
4.1.2 Global High-performance Liquid Chromatography (HPLC) Annual Revenue by Geographic Region (2020-2025)
4.2 World Historic High-performance Liquid Chromatography (HPLC) Market Size by Country/Region (2020-2025)
4.2.1 Global High-performance Liquid Chromatography (HPLC) Annual Sales by Country/Region (2020-2025)
4.2.2 Global High-performance Liquid Chromatography (HPLC) Annual Revenue by Country/Region (2020-2025)
4.3 Americas High-performance Liquid Chromatography (HPLC) Sales Growth
4.4 APAC High-performance Liquid Chromatography (HPLC) Sales Growth
4.5 Europe High-performance Liquid Chromatography (HPLC) Sales Growth
4.6 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales Growth
5 Americas
5.1 Americas High-performance Liquid Chromatography (HPLC) Sales by Country
5.1.1 Americas High-performance Liquid Chromatography (HPLC) Sales by Country (2020-2025)
5.1.2 Americas High-performance Liquid Chromatography (HPLC) Revenue by Country (2020-2025)
5.2 Americas High-performance Liquid Chromatography (HPLC) Sales by Type (2020-2025)
5.3 Americas High-performance Liquid Chromatography (HPLC) Sales by Application (2020-2025)
5.4 United States
5.5 Canada
5.6 Mexico
5.7 Brazil
6 APAC
6.1 APAC High-performance Liquid Chromatography (HPLC) Sales by Region
6.1.1 APAC High-performance Liquid Chromatography (HPLC) Sales by Region (2020-2025)
6.1.2 APAC High-performance Liquid Chromatography (HPLC) Revenue by Region (2020-2025)
6.2 APAC High-performance Liquid Chromatography (HPLC) Sales by Type (2020-2025)
6.3 APAC High-performance Liquid Chromatography (HPLC) Sales by Application (2020-2025)
6.4 China
6.5 Japan
6.6 South Korea
6.7 Southeast Asia
6.8 India
6.9 Australia
6.10 China Taiwan
7 Europe
7.1 Europe High-performance Liquid Chromatography (HPLC) by Country
7.1.1 Europe High-performance Liquid Chromatography (HPLC) Sales by Country (2020-2025)
7.1.2 Europe High-performance Liquid Chromatography (HPLC) Revenue by Country (2020-2025)
7.2 Europe High-performance Liquid Chromatography (HPLC) Sales by Type (2020-2025)
7.3 Europe High-performance Liquid Chromatography (HPLC) Sales by Application (2020-2025)
7.4 Germany
7.5 France
7.6 UK
7.7 Italy
7.8 Russia
8 Middle East & Africa
8.1 Middle East & Africa High-performance Liquid Chromatography (HPLC) by Country
8.1.1 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales by Country (2020-2025)
8.1.2 Middle East & Africa High-performance Liquid Chromatography (HPLC) Revenue by Country (2020-2025)
8.2 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales by Type (2020-2025)
8.3 Middle East & Africa High-performance Liquid Chromatography (HPLC) Sales by Application (2020-2025)
8.4 Egypt
8.5 South Africa
8.6 Israel
8.7 Turkey
8.8 GCC Countries
9 Market Drivers, Challenges and Trends
9.1 Market Drivers & Growth Opportunities
9.2 Market Challenges & Risks
9.3 Industry Trends
10 Manufacturing Cost Structure Analysis
10.1 Raw Material and Suppliers
10.2 Manufacturing Cost Structure Analysis of High-performance Liquid Chromatography (HPLC)
10.3 Manufacturing Process Analysis of High-performance Liquid Chromatography (HPLC)
10.4 Industry Chain Structure of High-performance Liquid Chromatography (HPLC)
11 Marketing, Distributors and Customer
11.1 Sales Channel
11.1.1 Direct Channels
11.1.2 Indirect Channels
11.2 High-performance Liquid Chromatography (HPLC) Distributors
11.3 High-performance Liquid Chromatography (HPLC) Customer
12 World Forecast Review for High-performance Liquid Chromatography (HPLC) by Geographic Region
12.1 Global High-performance Liquid Chromatography (HPLC) Market Size Forecast by Region
12.1.1 Global High-performance Liquid Chromatography (HPLC) Forecast by Region (2026-2031)
12.1.2 Global High-performance Liquid Chromatography (HPLC) Annual Revenue Forecast by Region (2026-2031)
12.2 Americas Forecast by Country (2026-2031)
12.3 APAC Forecast by Region (2026-2031)
12.4 Europe Forecast by Country (2026-2031)
12.5 Middle East & Africa Forecast by Country (2026-2031)
12.6 Global High-performance Liquid Chromatography (HPLC) Forecast by Type (2026-2031)
12.7 Global High-performance Liquid Chromatography (HPLC) Forecast by Application (2026-2031)
13 Key Players Analysis
13.1 Agilent
13.1.1 Agilent Company Information
13.1.2 Agilent High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.1.3 Agilent High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.1.4 Agilent Main Business Overview
13.1.5 Agilent Latest Developments
13.2 Waters
13.2.1 Waters Company Information
13.2.2 Waters High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.2.3 Waters High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.2.4 Waters Main Business Overview
13.2.5 Waters Latest Developments
13.3 Shimadzu
13.3.1 Shimadzu Company Information
13.3.2 Shimadzu High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.3.3 Shimadzu High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.3.4 Shimadzu Main Business Overview
13.3.5 Shimadzu Latest Developments
13.4 Thermo Fisher
13.4.1 Thermo Fisher Company Information
13.4.2 Thermo Fisher High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.4.3 Thermo Fisher High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.4.4 Thermo Fisher Main Business Overview
13.4.5 Thermo Fisher Latest Developments
13.5 PerkinElmer
13.5.1 PerkinElmer Company Information
13.5.2 PerkinElmer High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.5.3 PerkinElmer High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.5.4 PerkinElmer Main Business Overview
13.5.5 PerkinElmer Latest Developments
13.6 Hitachi
13.6.1 Hitachi Company Information
13.6.2 Hitachi High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.6.3 Hitachi High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.6.4 Hitachi Main Business Overview
13.6.5 Hitachi Latest Developments
13.7 Jasco
13.7.1 Jasco Company Information
13.7.2 Jasco High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.7.3 Jasco High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.7.4 Jasco Main Business Overview
13.7.5 Jasco Latest Developments
13.8 Knauer
13.8.1 Knauer Company Information
13.8.2 Knauer High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.8.3 Knauer High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.8.4 Knauer Main Business Overview
13.8.5 Knauer Latest Developments
13.9 Bekman
13.9.1 Bekman Company Information
13.9.2 Bekman High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.9.3 Bekman High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.9.4 Bekman Main Business Overview
13.9.5 Bekman Latest Developments
13.10 YoungLin
13.10.1 YoungLin Company Information
13.10.2 YoungLin High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.10.3 YoungLin High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.10.4 YoungLin Main Business Overview
13.10.5 YoungLin Latest Developments
13.11 GBC
13.11.1 GBC Company Information
13.11.2 GBC High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.11.3 GBC High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.11.4 GBC Main Business Overview
13.11.5 GBC Latest Developments
13.12 Gilson
13.12.1 Gilson Company Information
13.12.2 Gilson High-performance Liquid Chromatography (HPLC) Product Portfolios and Specifications
13.12.3 Gilson High-performance Liquid Chromatography (HPLC) Sales, Revenue, Price and Gross Margin (2020-2025)
13.12.4 Gilson Main Business Overview
13.12.5 Gilson Latest Developments
14 Research Findings and Conclusion
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