
The global Oligonucleotide API Manufacturing Services market size is predicted to grow from US$ 960 million in 2025 to US$ 1798 million in 2031; it is expected to grow at a CAGR of 11.0% from 2025 to 2031.
Oligonucleotide API manufacturing services focus on providing high-quality oligonucleotide synthesis, purification, and scalable production to meet the research and commercialization needs of the biopharmaceutical industry. These services cover the entire process from nucleic acid sequence design and process development to optimization and large-scale GMP (Good Manufacturing Practice) production, ensuring high purity, high yield, and consistency. The manufacturing process utilizes advanced solid-phase synthesis (SPPS) technology, combined with quality control measures such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) to ensure compliance with regulatory standards. Oligonucleotide APIs are widely used in gene therapy, vaccine development, mRNA therapeutics, and RNA interference (RNAi)-based treatments, driving advancements in precision medicine.
United States market for Oligonucleotide API Manufacturing Services is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
China market for Oligonucleotide API Manufacturing Services is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Europe market for Oligonucleotide API Manufacturing Services is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Global key Oligonucleotide API Manufacturing Services players cover Danaher(IDT), Merck, Eurofins Scientific, Thermo Fisher Scientific, Agilent Technologies, etc. In terms of revenue, the global two largest companies occupied for a share nearly % in 2024.
The “Oligonucleotide API Manufacturing Services Industry Forecast” looks at past sales and reviews total world Oligonucleotide API Manufacturing Services sales in 2024, providing a comprehensive analysis by region and market sector of projected Oligonucleotide API Manufacturing Services sales for 2025 through 2031. With Oligonucleotide API Manufacturing Services sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Oligonucleotide API Manufacturing Services industry.
This Insight Report provides a comprehensive analysis of the global Oligonucleotide API Manufacturing Services landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on Oligonucleotide API Manufacturing Services portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms’ unique position in an accelerating global Oligonucleotide API Manufacturing Services market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Oligonucleotide API Manufacturing Services and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Oligonucleotide API Manufacturing Services.
This report presents a comprehensive overview, market shares, and growth opportunities of Oligonucleotide API Manufacturing Services market by product type, application, key players and key regions and countries.
Segmentation by Type:
ASO
siRNA
miRNA
saRNA
Aptamer
Others
Segmentation by Application:
Pharmaceuticals
Scientific Research
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the company's coverage, product portfolio, its market penetration.
Danaher(IDT)
Merck
Eurofins Scientific
Thermo Fisher Scientific
Agilent Technologies
Nippon Shokubai
Eurogentec
Ajinomoto Bio-Pharma
PeptiStar
Bachem
CordenPharma
Guangzhou RiboBio
Hongene Biotech
WuXi AppTec
Veliter
Ribobay Pharma
ChemExpress
Asymchem
Please Note - This is an on demand report and will be delivered in 2 business days (48 hours) post payment.
1 Scope of the Report
1.1 Market Introduction
1.2 Years Considered
1.3 Research Objectives
1.4 Market Research Methodology
1.5 Research Process and Data Source
1.6 Economic Indicators
1.7 Currency Considered
1.8 Market Estimation Caveats
2 Executive Summary
2.1 World Market Overview
2.1.1 Global Oligonucleotide API Manufacturing Services Market Size (2020-2031)
2.1.2 Oligonucleotide API Manufacturing Services Market Size CAGR by Region (2020 VS 2024 VS 2031)
2.1.3 World Current & Future Analysis for Oligonucleotide API Manufacturing Services by Country/Region (2020, 2024 & 2031)
2.2 Oligonucleotide API Manufacturing Services Segment by Type
2.2.1 ASO
2.2.2 siRNA
2.2.3 miRNA
2.2.4 saRNA
2.2.5 Aptamer
2.2.6 Others
2.3 Oligonucleotide API Manufacturing Services Market Size by Type
2.3.1 Oligonucleotide API Manufacturing Services Market Size CAGR by Type (2020 VS 2024 VS 2031)
2.3.2 Global Oligonucleotide API Manufacturing Services Market Size Market Share by Type (2020-2025)
2.4 Oligonucleotide API Manufacturing Services Segment by Application
2.4.1 Pharmaceuticals
2.4.2 Scientific Research
2.5 Oligonucleotide API Manufacturing Services Market Size by Application
2.5.1 Oligonucleotide API Manufacturing Services Market Size CAGR by Application (2020 VS 2024 VS 2031)
2.5.2 Global Oligonucleotide API Manufacturing Services Market Size Market Share by Application (2020-2025)
3 Oligonucleotide API Manufacturing Services Market Size by Player
3.1 Oligonucleotide API Manufacturing Services Market Size Market Share by Player
3.1.1 Global Oligonucleotide API Manufacturing Services Revenue by Player (2020-2025)
3.1.2 Global Oligonucleotide API Manufacturing Services Revenue Market Share by Player (2020-2025)
3.2 Global Oligonucleotide API Manufacturing Services Key Players Head office and Products Offered
3.3 Market Concentration Rate Analysis
3.3.1 Competition Landscape Analysis
3.3.2 Concentration Ratio (CR3, CR5 and CR10) & (2023-2025)
3.4 New Products and Potential Entrants
3.5 Mergers & Acquisitions, Expansion
4 Oligonucleotide API Manufacturing Services by Region
4.1 Oligonucleotide API Manufacturing Services Market Size by Region (2020-2025)
4.2 Global Oligonucleotide API Manufacturing Services Annual Revenue by Country/Region (2020-2025)
4.3 Americas Oligonucleotide API Manufacturing Services Market Size Growth (2020-2025)
4.4 APAC Oligonucleotide API Manufacturing Services Market Size Growth (2020-2025)
4.5 Europe Oligonucleotide API Manufacturing Services Market Size Growth (2020-2025)
4.6 Middle East & Africa Oligonucleotide API Manufacturing Services Market Size Growth (2020-2025)
5 Americas
5.1 Americas Oligonucleotide API Manufacturing Services Market Size by Country (2020-2025)
5.2 Americas Oligonucleotide API Manufacturing Services Market Size by Type (2020-2025)
5.3 Americas Oligonucleotide API Manufacturing Services Market Size by Application (2020-2025)
5.4 United States
5.5 Canada
5.6 Mexico
5.7 Brazil
6 APAC
6.1 APAC Oligonucleotide API Manufacturing Services Market Size by Region (2020-2025)
6.2 APAC Oligonucleotide API Manufacturing Services Market Size by Type (2020-2025)
6.3 APAC Oligonucleotide API Manufacturing Services Market Size by Application (2020-2025)
6.4 China
6.5 Japan
6.6 South Korea
6.7 Southeast Asia
6.8 India
6.9 Australia
7 Europe
7.1 Europe Oligonucleotide API Manufacturing Services Market Size by Country (2020-2025)
7.2 Europe Oligonucleotide API Manufacturing Services Market Size by Type (2020-2025)
7.3 Europe Oligonucleotide API Manufacturing Services Market Size by Application (2020-2025)
7.4 Germany
7.5 France
7.6 UK
7.7 Italy
7.8 Russia
8 Middle East & Africa
8.1 Middle East & Africa Oligonucleotide API Manufacturing Services by Region (2020-2025)
8.2 Middle East & Africa Oligonucleotide API Manufacturing Services Market Size by Type (2020-2025)
8.3 Middle East & Africa Oligonucleotide API Manufacturing Services Market Size by Application (2020-2025)
8.4 Egypt
8.5 South Africa
8.6 Israel
8.7 Turkey
8.8 GCC Countries
9 Market Drivers, Challenges and Trends
9.1 Market Drivers & Growth Opportunities
9.2 Market Challenges & Risks
9.3 Industry Trends
10 Global Oligonucleotide API Manufacturing Services Market Forecast
10.1 Global Oligonucleotide API Manufacturing Services Forecast by Region (2026-2031)
10.1.1 Global Oligonucleotide API Manufacturing Services Forecast by Region (2026-2031)
10.1.2 Americas Oligonucleotide API Manufacturing Services Forecast
10.1.3 APAC Oligonucleotide API Manufacturing Services Forecast
10.1.4 Europe Oligonucleotide API Manufacturing Services Forecast
10.1.5 Middle East & Africa Oligonucleotide API Manufacturing Services Forecast
10.2 Americas Oligonucleotide API Manufacturing Services Forecast by Country (2026-2031)
10.2.1 United States Market Oligonucleotide API Manufacturing Services Forecast
10.2.2 Canada Market Oligonucleotide API Manufacturing Services Forecast
10.2.3 Mexico Market Oligonucleotide API Manufacturing Services Forecast
10.2.4 Brazil Market Oligonucleotide API Manufacturing Services Forecast
10.3 APAC Oligonucleotide API Manufacturing Services Forecast by Region (2026-2031)
10.3.1 China Oligonucleotide API Manufacturing Services Market Forecast
10.3.2 Japan Market Oligonucleotide API Manufacturing Services Forecast
10.3.3 Korea Market Oligonucleotide API Manufacturing Services Forecast
10.3.4 Southeast Asia Market Oligonucleotide API Manufacturing Services Forecast
10.3.5 India Market Oligonucleotide API Manufacturing Services Forecast
10.3.6 Australia Market Oligonucleotide API Manufacturing Services Forecast
10.4 Europe Oligonucleotide API Manufacturing Services Forecast by Country (2026-2031)
10.4.1 Germany Market Oligonucleotide API Manufacturing Services Forecast
10.4.2 France Market Oligonucleotide API Manufacturing Services Forecast
10.4.3 UK Market Oligonucleotide API Manufacturing Services Forecast
10.4.4 Italy Market Oligonucleotide API Manufacturing Services Forecast
10.4.5 Russia Market Oligonucleotide API Manufacturing Services Forecast
10.5 Middle East & Africa Oligonucleotide API Manufacturing Services Forecast by Region (2026-2031)
10.5.1 Egypt Market Oligonucleotide API Manufacturing Services Forecast
10.5.2 South Africa Market Oligonucleotide API Manufacturing Services Forecast
10.5.3 Israel Market Oligonucleotide API Manufacturing Services Forecast
10.5.4 Turkey Market Oligonucleotide API Manufacturing Services Forecast
10.6 Global Oligonucleotide API Manufacturing Services Forecast by Type (2026-2031)
10.7 Global Oligonucleotide API Manufacturing Services Forecast by Application (2026-2031)
10.7.1 GCC Countries Market Oligonucleotide API Manufacturing Services Forecast
11 Key Players Analysis
11.1 Danaher(IDT)
11.1.1 Danaher(IDT) Company Information
11.1.2 Danaher(IDT) Oligonucleotide API Manufacturing Services Product Offered
11.1.3 Danaher(IDT) Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.1.4 Danaher(IDT) Main Business Overview
11.1.5 Danaher(IDT) Latest Developments
11.2 Merck
11.2.1 Merck Company Information
11.2.2 Merck Oligonucleotide API Manufacturing Services Product Offered
11.2.3 Merck Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.2.4 Merck Main Business Overview
11.2.5 Merck Latest Developments
11.3 Eurofins Scientific
11.3.1 Eurofins Scientific Company Information
11.3.2 Eurofins Scientific Oligonucleotide API Manufacturing Services Product Offered
11.3.3 Eurofins Scientific Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.3.4 Eurofins Scientific Main Business Overview
11.3.5 Eurofins Scientific Latest Developments
11.4 Thermo Fisher Scientific
11.4.1 Thermo Fisher Scientific Company Information
11.4.2 Thermo Fisher Scientific Oligonucleotide API Manufacturing Services Product Offered
11.4.3 Thermo Fisher Scientific Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.4.4 Thermo Fisher Scientific Main Business Overview
11.4.5 Thermo Fisher Scientific Latest Developments
11.5 Agilent Technologies
11.5.1 Agilent Technologies Company Information
11.5.2 Agilent Technologies Oligonucleotide API Manufacturing Services Product Offered
11.5.3 Agilent Technologies Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.5.4 Agilent Technologies Main Business Overview
11.5.5 Agilent Technologies Latest Developments
11.6 Nippon Shokubai
11.6.1 Nippon Shokubai Company Information
11.6.2 Nippon Shokubai Oligonucleotide API Manufacturing Services Product Offered
11.6.3 Nippon Shokubai Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.6.4 Nippon Shokubai Main Business Overview
11.6.5 Nippon Shokubai Latest Developments
11.7 Eurogentec
11.7.1 Eurogentec Company Information
11.7.2 Eurogentec Oligonucleotide API Manufacturing Services Product Offered
11.7.3 Eurogentec Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.7.4 Eurogentec Main Business Overview
11.7.5 Eurogentec Latest Developments
11.8 Ajinomoto Bio-Pharma
11.8.1 Ajinomoto Bio-Pharma Company Information
11.8.2 Ajinomoto Bio-Pharma Oligonucleotide API Manufacturing Services Product Offered
11.8.3 Ajinomoto Bio-Pharma Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.8.4 Ajinomoto Bio-Pharma Main Business Overview
11.8.5 Ajinomoto Bio-Pharma Latest Developments
11.9 PeptiStar
11.9.1 PeptiStar Company Information
11.9.2 PeptiStar Oligonucleotide API Manufacturing Services Product Offered
11.9.3 PeptiStar Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.9.4 PeptiStar Main Business Overview
11.9.5 PeptiStar Latest Developments
11.10 Bachem
11.10.1 Bachem Company Information
11.10.2 Bachem Oligonucleotide API Manufacturing Services Product Offered
11.10.3 Bachem Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.10.4 Bachem Main Business Overview
11.10.5 Bachem Latest Developments
11.11 CordenPharma
11.11.1 CordenPharma Company Information
11.11.2 CordenPharma Oligonucleotide API Manufacturing Services Product Offered
11.11.3 CordenPharma Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.11.4 CordenPharma Main Business Overview
11.11.5 CordenPharma Latest Developments
11.12 Guangzhou RiboBio
11.12.1 Guangzhou RiboBio Company Information
11.12.2 Guangzhou RiboBio Oligonucleotide API Manufacturing Services Product Offered
11.12.3 Guangzhou RiboBio Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.12.4 Guangzhou RiboBio Main Business Overview
11.12.5 Guangzhou RiboBio Latest Developments
11.13 Hongene Biotech
11.13.1 Hongene Biotech Company Information
11.13.2 Hongene Biotech Oligonucleotide API Manufacturing Services Product Offered
11.13.3 Hongene Biotech Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.13.4 Hongene Biotech Main Business Overview
11.13.5 Hongene Biotech Latest Developments
11.14 WuXi AppTec
11.14.1 WuXi AppTec Company Information
11.14.2 WuXi AppTec Oligonucleotide API Manufacturing Services Product Offered
11.14.3 WuXi AppTec Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.14.4 WuXi AppTec Main Business Overview
11.14.5 WuXi AppTec Latest Developments
11.15 Veliter
11.15.1 Veliter Company Information
11.15.2 Veliter Oligonucleotide API Manufacturing Services Product Offered
11.15.3 Veliter Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.15.4 Veliter Main Business Overview
11.15.5 Veliter Latest Developments
11.16 Ribobay Pharma
11.16.1 Ribobay Pharma Company Information
11.16.2 Ribobay Pharma Oligonucleotide API Manufacturing Services Product Offered
11.16.3 Ribobay Pharma Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.16.4 Ribobay Pharma Main Business Overview
11.16.5 Ribobay Pharma Latest Developments
11.17 ChemExpress
11.17.1 ChemExpress Company Information
11.17.2 ChemExpress Oligonucleotide API Manufacturing Services Product Offered
11.17.3 ChemExpress Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.17.4 ChemExpress Main Business Overview
11.17.5 ChemExpress Latest Developments
11.18 Asymchem
11.18.1 Asymchem Company Information
11.18.2 Asymchem Oligonucleotide API Manufacturing Services Product Offered
11.18.3 Asymchem Oligonucleotide API Manufacturing Services Revenue, Gross Margin and Market Share (2020-2025)
11.18.4 Asymchem Main Business Overview
11.18.5 Asymchem Latest Developments
12 Research Findings and Conclusion
*If Applicable.
