

A buffer solution is comprised of a weak conjugate acid-base pair, for example, a weak acid and its conjugate base, or a weak base and its conjugate acid. Small quantities of other acids or bases are neutralized when added to the solution, and as a result, the solution resists changes in pH. Solutions with stable pH are required for the processing of protein-based biologic APIs because of their sensitivity to changes in pH. The stable pH range and capacity (the amount of acid/base that can be added without a change in pH) of a buffer are determined by the conjugate acid-base pair.
Most purification steps for downstream processing of biologics require buffers to equilibrate, condition, wash, elute, or concentrate the product. They are used in product isolation and purification steps to facilitate protein capture and polishing and also in the filtration process for the removal of viruses or depyrogenation. Aqueous solutions are also required for cleaning and disinfecting downstream processing equipment, such as chromatography matrices and membrane filtration systems. The main equipment involved in downstream processing with buffers includes mixers for buffer preparation, as well as equipment for purification, including packed-bed chromatography systems, fluidized beds, ultrafiltration and diafiltration membranes, microfiltration membranes, depth filtration cartridges, and virus-removal systems.
The global Biopharma Buffer market was valued at US$ 841 million in 2023 and is anticipated to reach US$ 1068.2 million by 2030, witnessing a CAGR of 3.4% during the forecast period 2024-2030.
The global pharmaceutical market is 1475 billion USD in 2022, growing at a CAGR of 5% during the next six years. The pharmaceutical market includes chemical drugs and biological drugs. For biologics is expected to 381 billion USD in 2022. In comparison, the chemical drug market is estimated to increase from 1005 billion in 2018 to 1094 billion U.S. dollars in 2022. The pharmaceutical market factors such as increasing demand for healthcare, technological advancements, and the rising prevalence of chronic diseases, increase in funding from private & government organizations for development of pharmaceutical manufacturing segments and rise in R&D activities for drugs. However, the industry also faces challenges such as stringent regulations, high costs of research and development, and patent expirations. Companies need to continuously innovate and adapt to these challenges to stay competitive in the market and ensure their products reach patients in need. Additionally, the COVID-19 pandemic has highlighted the importance of vaccine development and supply chain management, further emphasizing the need for pharmaceutical companies to be agile and responsive to emerging public health needs.
This report aims to provide a comprehensive presentation of the global market for Biopharma Buffer, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Biopharma Buffer.
Report Scope
The Biopharma Buffer market size, estimations, and forecasts are provided in terms of sales volume (KL) and revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Biopharma Buffer market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Biopharma Buffer manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Avantor
Alfa Aesar (Thermo Fisher)
Merck
Lonza
Bio-Rad
BD
GE Healthcare
Promega Corporation
Hamilton Company
XZL BIO-TECHNOLOGY
SRL
Segment by Type
Phosphates Type
Acetates Type
TRIS Type
Others
Segment by Application
Research Institution
Pharmaceutical Industry
Others
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Indonesia
Thailand
Malaysia
Latin America
Mexico
Brazil
Argentina
Middle East & Africa
Turkey
Saudi Arabia
UAE
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of Biopharma Buffer manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Sales, revenue of Biopharma Buffer in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 8: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 9: The main points and conclusions of the report.
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1 Biopharma Buffer Market Overview
1.1 Product Overview and Scope of Biopharma Buffer
1.2 Biopharma Buffer Segment by Type
1.2.1 Global Biopharma Buffer Market Value Comparison by Type (2024-2030)
1.2.2 Phosphates Type
1.2.3 Acetates Type
1.2.4 TRIS Type
1.2.5 Others
1.3 Biopharma Buffer Segment by Application
1.3.1 Global Biopharma Buffer Market Value by Application: (2024-2030)
1.3.2 Research Institution
1.3.3 Pharmaceutical Industry
1.3.4 Others
1.4 Global Biopharma Buffer Market Size Estimates and Forecasts
1.4.1 Global Biopharma Buffer Revenue 2019-2030
1.4.2 Global Biopharma Buffer Sales 2019-2030
1.4.3 Global Biopharma Buffer Market Average Price (2019-2030)
1.5 Assumptions and Limitations
2 Biopharma Buffer Market Competition by Manufacturers
2.1 Global Biopharma Buffer Sales Market Share by Manufacturers (2019-2024)
2.2 Global Biopharma Buffer Revenue Market Share by Manufacturers (2019-2024)
2.3 Global Biopharma Buffer Average Price by Manufacturers (2019-2024)
2.4 Global Biopharma Buffer Industry Ranking 2022 VS 2023 VS 2024
2.5 Global Key Manufacturers of Biopharma Buffer, Manufacturing Sites & Headquarters
2.6 Global Key Manufacturers of Biopharma Buffer, Product Type & Application
2.7 Biopharma Buffer Market Competitive Situation and Trends
2.7.1 Biopharma Buffer Market Concentration Rate
2.7.2 The Global Top 5 and Top 10 Largest Biopharma Buffer Players Market Share by Revenue
2.7.3 Global Biopharma Buffer Market Share by Company Type (Tier 1, Tier 2 and Tier 3)
2.8 Manufacturers Mergers & Acquisitions, Expansion Plans
3 Biopharma Buffer Retrospective Market Scenario by Region
3.1 Global Biopharma Buffer Market Size by Region: 2019 Versus 2023 Versus 2030
3.2 Global Biopharma Buffer Global Biopharma Buffer Sales by Region: 2019-2030
3.2.1 Global Biopharma Buffer Sales by Region: 2019-2024
3.2.2 Global Biopharma Buffer Sales by Region: 2025-2030
3.3 Global Biopharma Buffer Global Biopharma Buffer Revenue by Region: 2019-2030
3.3.1 Global Biopharma Buffer Revenue by Region: 2019-2024
3.3.2 Global Biopharma Buffer Revenue by Region: 2025-2030
3.4 North America Biopharma Buffer Market Facts & Figures by Country
3.4.1 North America Biopharma Buffer Market Size by Country: 2019 VS 2023 VS 2030
3.4.2 North America Biopharma Buffer Sales by Country (2019-2030)
3.4.3 North America Biopharma Buffer Revenue by Country (2019-2030)
3.4.4 United States
3.4.5 Canada
3.5 Europe Biopharma Buffer Market Facts & Figures by Country
3.5.1 Europe Biopharma Buffer Market Size by Country: 2019 VS 2023 VS 2030
3.5.2 Europe Biopharma Buffer Sales by Country (2019-2030)
3.5.3 Europe Biopharma Buffer Revenue by Country (2019-2030)
3.5.4 Germany
3.5.5 France
3.5.6 U.K.
3.5.7 Italy
3.5.8 Russia
3.6 Asia Pacific Biopharma Buffer Market Facts & Figures by Country
3.6.1 Asia Pacific Biopharma Buffer Market Size by Country: 2019 VS 2023 VS 2030
3.6.2 Asia Pacific Biopharma Buffer Sales by Country (2019-2030)
3.6.3 Asia Pacific Biopharma Buffer Revenue by Country (2019-2030)
3.6.4 China
3.6.5 Japan
3.6.6 South Korea
3.6.7 India
3.6.8 Australia
3.6.9 China Taiwan
3.6.10 Indonesia
3.6.11 Thailand
3.6.12 Malaysia
3.7 Latin America Biopharma Buffer Market Facts & Figures by Country
3.7.1 Latin America Biopharma Buffer Market Size by Country: 2019 VS 2023 VS 2030
3.7.2 Latin America Biopharma Buffer Sales by Country (2019-2030)
3.7.3 Latin America Biopharma Buffer Revenue by Country (2019-2030)
3.7.4 Mexico
3.7.5 Brazil
3.7.6 Argentina
3.8 Middle East and Africa Biopharma Buffer Market Facts & Figures by Country
3.8.1 Middle East and Africa Biopharma Buffer Market Size by Country: 2019 VS 2023 VS 2030
3.8.2 Middle East and Africa Biopharma Buffer Sales by Country (2019-2030)
3.8.3 Middle East and Africa Biopharma Buffer Revenue by Country (2019-2030)
3.8.4 Turkey
3.8.5 Saudi Arabia
3.8.6 UAE
4 Segment by Type
4.1 Global Biopharma Buffer Sales by Type (2019-2030)
4.1.1 Global Biopharma Buffer Sales by Type (2019-2024)
4.1.2 Global Biopharma Buffer Sales by Type (2025-2030)
4.1.3 Global Biopharma Buffer Sales Market Share by Type (2019-2030)
4.2 Global Biopharma Buffer Revenue by Type (2019-2030)
4.2.1 Global Biopharma Buffer Revenue by Type (2019-2024)
4.2.2 Global Biopharma Buffer Revenue by Type (2025-2030)
4.2.3 Global Biopharma Buffer Revenue Market Share by Type (2019-2030)
4.3 Global Biopharma Buffer Price by Type (2019-2030)
5 Segment by Application
5.1 Global Biopharma Buffer Sales by Application (2019-2030)
5.1.1 Global Biopharma Buffer Sales by Application (2019-2024)
5.1.2 Global Biopharma Buffer Sales by Application (2025-2030)
5.1.3 Global Biopharma Buffer Sales Market Share by Application (2019-2030)
5.2 Global Biopharma Buffer Revenue by Application (2019-2030)
5.2.1 Global Biopharma Buffer Revenue by Application (2019-2024)
5.2.2 Global Biopharma Buffer Revenue by Application (2025-2030)
5.2.3 Global Biopharma Buffer Revenue Market Share by Application (2019-2030)
5.3 Global Biopharma Buffer Price by Application (2019-2030)
6 Key Companies Profiled
6.1 Avantor
6.1.1 Avantor Corporation Information
6.1.2 Avantor Description and Business Overview
6.1.3 Avantor Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.1.4 Avantor Biopharma Buffer Product Portfolio
6.1.5 Avantor Recent Developments/Updates
6.2 Alfa Aesar (Thermo Fisher)
6.2.1 Alfa Aesar (Thermo Fisher) Corporation Information
6.2.2 Alfa Aesar (Thermo Fisher) Description and Business Overview
6.2.3 Alfa Aesar (Thermo Fisher) Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.2.4 Alfa Aesar (Thermo Fisher) Biopharma Buffer Product Portfolio
6.2.5 Alfa Aesar (Thermo Fisher) Recent Developments/Updates
6.3 Merck
6.3.1 Merck Corporation Information
6.3.2 Merck Description and Business Overview
6.3.3 Merck Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.3.4 Merck Biopharma Buffer Product Portfolio
6.3.5 Merck Recent Developments/Updates
6.4 Lonza
6.4.1 Lonza Corporation Information
6.4.2 Lonza Description and Business Overview
6.4.3 Lonza Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.4.4 Lonza Biopharma Buffer Product Portfolio
6.4.5 Lonza Recent Developments/Updates
6.5 Bio-Rad
6.5.1 Bio-Rad Corporation Information
6.5.2 Bio-Rad Description and Business Overview
6.5.3 Bio-Rad Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.5.4 Bio-Rad Biopharma Buffer Product Portfolio
6.5.5 Bio-Rad Recent Developments/Updates
6.6 BD
6.6.1 BD Corporation Information
6.6.2 BD Description and Business Overview
6.6.3 BD Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.6.4 BD Biopharma Buffer Product Portfolio
6.6.5 BD Recent Developments/Updates
6.7 GE Healthcare
6.6.1 GE Healthcare Corporation Information
6.6.2 GE Healthcare Description and Business Overview
6.6.3 GE Healthcare Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.4.4 GE Healthcare Biopharma Buffer Product Portfolio
6.7.5 GE Healthcare Recent Developments/Updates
6.8 Promega Corporation
6.8.1 Promega Corporation Corporation Information
6.8.2 Promega Corporation Description and Business Overview
6.8.3 Promega Corporation Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.8.4 Promega Corporation Biopharma Buffer Product Portfolio
6.8.5 Promega Corporation Recent Developments/Updates
6.9 Hamilton Company
6.9.1 Hamilton Company Corporation Information
6.9.2 Hamilton Company Description and Business Overview
6.9.3 Hamilton Company Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.9.4 Hamilton Company Biopharma Buffer Product Portfolio
6.9.5 Hamilton Company Recent Developments/Updates
6.10 XZL BIO-TECHNOLOGY
6.10.1 XZL BIO-TECHNOLOGY Corporation Information
6.10.2 XZL BIO-TECHNOLOGY Description and Business Overview
6.10.3 XZL BIO-TECHNOLOGY Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.10.4 XZL BIO-TECHNOLOGY Biopharma Buffer Product Portfolio
6.10.5 XZL BIO-TECHNOLOGY Recent Developments/Updates
6.11 SRL
6.11.1 SRL Corporation Information
6.11.2 SRL Biopharma Buffer Description and Business Overview
6.11.3 SRL Biopharma Buffer Sales, Revenue and Gross Margin (2019-2024)
6.11.4 SRL Biopharma Buffer Product Portfolio
6.11.5 SRL Recent Developments/Updates
7 Industry Chain and Sales Channels Analysis
7.1 Biopharma Buffer Industry Chain Analysis
7.2 Biopharma Buffer Key Raw Materials
7.2.1 Key Raw Materials
7.2.2 Raw Materials Key Suppliers
7.3 Biopharma Buffer Production Mode & Process
7.4 Biopharma Buffer Sales and Marketing
7.4.1 Biopharma Buffer Sales Channels
7.4.2 Biopharma Buffer Distributors
7.5 Biopharma Buffer Customers
8 Biopharma Buffer Market Dynamics
8.1 Biopharma Buffer Industry Trends
8.2 Biopharma Buffer Market Drivers
8.3 Biopharma Buffer Market Challenges
8.4 Biopharma Buffer Market Restraints
9 Research Finding and Conclusion
10 Methodology and Data Source
10.1 Methodology/Research Approach
10.1.1 Research Programs/Design
10.1.2 Market Size Estimation
10.1.3 Market Breakdown and Data Triangulation
10.2 Data Source
10.2.1 Secondary Sources
10.2.2 Primary Sources
10.3 Author List
10.4 Disclaimer
Avantor
Alfa Aesar (Thermo Fisher)
Merck
Lonza
Bio-Rad
BD
GE Healthcare
Promega Corporation
Hamilton Company
XZL BIO-TECHNOLOGY
SRL
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*If Applicable.