The global market for High-performance Liquid Chromatography (HPLC) was valued at US$ 3529 million in the year 2024 and is projected to reach a revised size of US$ 4416 million by 2031, growing at a CAGR of 3.3% during the forecast period.
The 2025 U.S. tariff policies introduce profound uncertainty into the global economic landscape. This report critically examines the implications of recent tariff adjustments and international strategic countermeasures on High-performance Liquid Chromatography (HPLC) competitive dynamics, regional economic interdependencies, and supply chain reconfigurations.
High-performance liquid chromatography (HPLC) is a technique in analytic chemistry used to separate the components in a mixture, to identify each component, and to quantify each component. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.
Market Development Opportunities & Main Driving Factors
Driven by the growing need for high-precision and high-throughput analytical methods in pharmaceuticals, biotechnology, food safety, and environmental monitoring, the HPLC market is experiencing steady expansion. Particularly in drug discovery, biologics analysis, and metabolomics research, HPLC has become a core analytical tool. Additionally, stricter regulatory standards for pharmaceuticals, food products, and environmental safety are prompting greater investment in advanced analytical instruments, thereby boosting market growth.
Market Challenges, Risks, & Restraints
Despite its promising outlook, the HPLC sector faces challenges such as high equipment costs, complex operation and maintenance requirements, and a shortage of skilled professionals鈥攅specially in emerging markets. Moreover, the risk of technological substitution must be considered, with newer techniques like Ultra Performance Liquid Chromatography (UPLC) potentially replacing conventional HPLC systems in some applications, reshaping the market landscape.
Downstream Demand Trends
Downstream demand is shifting from traditional pharmaceutical testing to more diversified applications, including biopharmaceuticals, food additives, cosmetic ingredients, and environmental toxins. With the rise of precision medicine and personalized therapies, clinical sample analysis and pharmacokinetic studies are driving continued demand for HPLC systems with higher sensitivity and advanced data processing capabilities.
EU is the largest High-performance Liquid Chromatography (HPLC) market with about 34% market share. US is follower, accounting for about 34% market share. The key players are Agilent, Waters, Shimadzu, Thermo Fisher, PerkinElmer, Hitachi, Jasco, Knauer, Bekman, YoungLin, GBC, Gilson etc. Top 3 companies occupied about 66% market share.
Report Scope
This report aims to provide a comprehensive presentation of the global market for High-performance Liquid Chromatography (HPLC), with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding High-performance Liquid Chromatography (HPLC).
The High-performance Liquid Chromatography (HPLC) market size, estimations, and forecasts are provided in terms of output/shipments (K Units) and revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. This report segments the global High-performance Liquid Chromatography (HPLC) market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the High-performance Liquid Chromatography (HPLC) manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, production, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
By Company
Agilent
Waters
Shimadzu
Thermo Fisher
PerkinElmer
Hitachi
Jasco
Knauer
Bekman
YoungLin
GBC
Gilson
Segment by Type
UVS
FD
RID
ED
CD
Segment by Application
Pharmacy
Biotechnology
CROs
Academia
Chemicals
Others
Production by Region
North America
Europe
Japan
China
Consumption by Region
North America
U.S.
Canada
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Indonesia
Thailand
Malaysia
Philippines
Vietnam
Europe
Germany
France
U.K.
Italy
Russia
Latin America
Mexico
Brazil
Argentina
Middle East and Africa
Turkey
Saudi Arabia
U.A.E
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of High-performance Liquid Chromatography (HPLC) manufacturers competitive landscape, price, production and value market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Production/output, value of High-performance Liquid Chromatography (HPLC) by region/country. It provides a quantitative analysis of the market size and development potential of each region in the next six years.
Chapter 4: Consumption of High-performance Liquid Chromatography (HPLC) in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and production of each country in the world.
Chapter 5: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 6: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product production/output, value, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 10: The main points and conclusions of the report.
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1 High-performance Liquid Chromatography (HPLC) Market Overview
1.1 Product Definition
1.2 High-performance Liquid Chromatography (HPLC) by Type
1.2.1 Global High-performance Liquid Chromatography (HPLC) Market Value Growth Rate Analysis by Type: 2024 VS 2031
1.2.2 UVS
1.2.3 FD
1.2.4 RID
1.2.5 ED
1.2.6 CD
1.3 High-performance Liquid Chromatography (HPLC) by Application
1.3.1 Global High-performance Liquid Chromatography (HPLC) Market Value Growth Rate Analysis by Application: 2024 VS 2031
1.3.2 Pharmacy
1.3.3 Biotechnology
1.3.4 CROs
1.3.5 Academia
1.3.6 Chemicals
1.3.7 Others
1.4 Global Market Growth Prospects
1.4.1 Global High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts (2020-2031)
1.4.2 Global High-performance Liquid Chromatography (HPLC) Production Capacity Estimates and Forecasts (2020-2031)
1.4.3 Global High-performance Liquid Chromatography (HPLC) Production Estimates and Forecasts (2020-2031)
1.4.4 Global High-performance Liquid Chromatography (HPLC) Market Average Price Estimates and Forecasts (2020-2031)
1.5 Assumptions and Limitations
2 Market Competition by Manufacturers
2.1 Global High-performance Liquid Chromatography (HPLC) Production Market Share by Manufacturers (2020-2025)
2.2 Global High-performance Liquid Chromatography (HPLC) Production Value Market Share by Manufacturers (2020-2025)
2.3 Global Key Players of High-performance Liquid Chromatography (HPLC), Industry Ranking, 2023 VS 2024
2.4 Global High-performance Liquid Chromatography (HPLC) Company Type and Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
2.5 Global High-performance Liquid Chromatography (HPLC) Average Price by Manufacturers (2020-2025)
2.6 Global Key Manufacturers of High-performance Liquid Chromatography (HPLC), Manufacturing Base Distribution and Headquarters
2.7 Global Key Manufacturers of High-performance Liquid Chromatography (HPLC), Product Offered and Application
2.8 Global Key Manufacturers of High-performance Liquid Chromatography (HPLC), Date of Enter into This Industry
2.9 High-performance Liquid Chromatography (HPLC) Market Competitive Situation and Trends
2.9.1 High-performance Liquid Chromatography (HPLC) Market Concentration Rate
2.9.2 Global 5 and 10 Largest High-performance Liquid Chromatography (HPLC) Players Market Share by Revenue
2.10 Mergers & Acquisitions, Expansion
3 High-performance Liquid Chromatography (HPLC) Production by Region
3.1 Global High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
3.2 Global High-performance Liquid Chromatography (HPLC) Production Value by Region (2020-2031)
3.2.1 Global High-performance Liquid Chromatography (HPLC) Production Value by Region (2020-2025)
3.2.2 Global Forecasted Production Value of High-performance Liquid Chromatography (HPLC) by Region (2026-2031)
3.3 Global High-performance Liquid Chromatography (HPLC) Production Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
3.4 Global High-performance Liquid Chromatography (HPLC) Production Volume by Region (2020-2031)
3.4.1 Global High-performance Liquid Chromatography (HPLC) Production by Region (2020-2025)
3.4.2 Global Forecasted Production of High-performance Liquid Chromatography (HPLC) by Region (2026-2031)
3.5 Global High-performance Liquid Chromatography (HPLC) Market Price Analysis by Region (2020-2025)
3.6 Global High-performance Liquid Chromatography (HPLC) Production and Value, Year-over-Year Growth
3.6.1 North America High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts (2020-2031)
3.6.2 Europe High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts (2020-2031)
3.6.3 Japan High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts (2020-2031)
3.6.4 China High-performance Liquid Chromatography (HPLC) Production Value Estimates and Forecasts (2020-2031)
4 High-performance Liquid Chromatography (HPLC) Consumption by Region
4.1 Global High-performance Liquid Chromatography (HPLC) Consumption Estimates and Forecasts by Region: 2020 VS 2024 VS 2031
4.2 Global High-performance Liquid Chromatography (HPLC) Consumption by Region (2020-2031)
4.2.1 Global High-performance Liquid Chromatography (HPLC) Consumption by Region (2020-2025)
4.2.2 Global High-performance Liquid Chromatography (HPLC) Forecasted Consumption by Region (2026-2031)
4.3 North America
4.3.1 North America High-performance Liquid Chromatography (HPLC) Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.3.2 North America High-performance Liquid Chromatography (HPLC) Consumption by Country (2020-2031)
4.3.3 U.S.
4.3.4 Canada
4.4 Europe
4.4.1 Europe High-performance Liquid Chromatography (HPLC) Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.4.2 Europe High-performance Liquid Chromatography (HPLC) Consumption by Country (2020-2031)
4.4.3 Germany
4.4.4 France
4.4.5 U.K.
4.4.6 Italy
4.4.7 Netherlands
4.5 Asia Pacific
4.5.1 Asia Pacific High-performance Liquid Chromatography (HPLC) Consumption Growth Rate by Region: 2020 VS 2024 VS 2031
4.5.2 Asia Pacific High-performance Liquid Chromatography (HPLC) Consumption by Region (2020-2031)
4.5.3 China
4.5.4 Japan
4.5.5 South Korea
4.5.6 China Taiwan
4.5.7 Southeast Asia
4.5.8 India
4.6 Latin America, Middle East & Africa
4.6.1 Latin America, Middle East & Africa High-performance Liquid Chromatography (HPLC) Consumption Growth Rate by Country: 2020 VS 2024 VS 2031
4.6.2 Latin America, Middle East & Africa High-performance Liquid Chromatography (HPLC) Consumption by Country (2020-2031)
4.6.3 Mexico
4.6.4 Brazil
4.6.5 Turkey
4.6.6 GCC Countries
5 Segment by Type
5.1 Global High-performance Liquid Chromatography (HPLC) Production by Type (2020-2031)
5.1.1 Global High-performance Liquid Chromatography (HPLC) Production by Type (2020-2025)
5.1.2 Global High-performance Liquid Chromatography (HPLC) Production by Type (2026-2031)
5.1.3 Global High-performance Liquid Chromatography (HPLC) Production Market Share by Type (2020-2031)
5.2 Global High-performance Liquid Chromatography (HPLC) Production Value by Type (2020-2031)
5.2.1 Global High-performance Liquid Chromatography (HPLC) Production Value by Type (2020-2025)
5.2.2 Global High-performance Liquid Chromatography (HPLC) Production Value by Type (2026-2031)
5.2.3 Global High-performance Liquid Chromatography (HPLC) Production Value Market Share by Type (2020-2031)
5.3 Global High-performance Liquid Chromatography (HPLC) Price by Type (2020-2031)
6 Segment by Application
6.1 Global High-performance Liquid Chromatography (HPLC) Production by Application (2020-2031)
6.1.1 Global High-performance Liquid Chromatography (HPLC) Production by Application (2020-2025)
6.1.2 Global High-performance Liquid Chromatography (HPLC) Production by Application (2026-2031)
6.1.3 Global High-performance Liquid Chromatography (HPLC) Production Market Share by Application (2020-2031)
6.2 Global High-performance Liquid Chromatography (HPLC) Production Value by Application (2020-2031)
6.2.1 Global High-performance Liquid Chromatography (HPLC) Production Value by Application (2020-2025)
6.2.2 Global High-performance Liquid Chromatography (HPLC) Production Value by Application (2026-2031)
6.2.3 Global High-performance Liquid Chromatography (HPLC) Production Value Market Share by Application (2020-2031)
6.3 Global High-performance Liquid Chromatography (HPLC) Price by Application (2020-2031)
7 Key Companies Profiled
7.1 Agilent
7.1.1 Agilent High-performance Liquid Chromatography (HPLC) Company Information
7.1.2 Agilent High-performance Liquid Chromatography (HPLC) Product Portfolio
7.1.3 Agilent High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.1.4 Agilent Main Business and Markets Served
7.1.5 Agilent Recent Developments/Updates
7.2 Waters
7.2.1 Waters High-performance Liquid Chromatography (HPLC) Company Information
7.2.2 Waters High-performance Liquid Chromatography (HPLC) Product Portfolio
7.2.3 Waters High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.2.4 Waters Main Business and Markets Served
7.2.5 Waters Recent Developments/Updates
7.3 Shimadzu
7.3.1 Shimadzu High-performance Liquid Chromatography (HPLC) Company Information
7.3.2 Shimadzu High-performance Liquid Chromatography (HPLC) Product Portfolio
7.3.3 Shimadzu High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.3.4 Shimadzu Main Business and Markets Served
7.3.5 Shimadzu Recent Developments/Updates
7.4 Thermo Fisher
7.4.1 Thermo Fisher High-performance Liquid Chromatography (HPLC) Company Information
7.4.2 Thermo Fisher High-performance Liquid Chromatography (HPLC) Product Portfolio
7.4.3 Thermo Fisher High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.4.4 Thermo Fisher Main Business and Markets Served
7.4.5 Thermo Fisher Recent Developments/Updates
7.5 PerkinElmer
7.5.1 PerkinElmer High-performance Liquid Chromatography (HPLC) Company Information
7.5.2 PerkinElmer High-performance Liquid Chromatography (HPLC) Product Portfolio
7.5.3 PerkinElmer High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.5.4 PerkinElmer Main Business and Markets Served
7.5.5 PerkinElmer Recent Developments/Updates
7.6 Hitachi
7.6.1 Hitachi High-performance Liquid Chromatography (HPLC) Company Information
7.6.2 Hitachi High-performance Liquid Chromatography (HPLC) Product Portfolio
7.6.3 Hitachi High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.6.4 Hitachi Main Business and Markets Served
7.6.5 Hitachi Recent Developments/Updates
7.7 Jasco
7.7.1 Jasco High-performance Liquid Chromatography (HPLC) Company Information
7.7.2 Jasco High-performance Liquid Chromatography (HPLC) Product Portfolio
7.7.3 Jasco High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.7.4 Jasco Main Business and Markets Served
7.7.5 Jasco Recent Developments/Updates
7.8 Knauer
7.8.1 Knauer High-performance Liquid Chromatography (HPLC) Company Information
7.8.2 Knauer High-performance Liquid Chromatography (HPLC) Product Portfolio
7.8.3 Knauer High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.8.4 Knauer Main Business and Markets Served
7.8.5 Knauer Recent Developments/Updates
7.9 Bekman
7.9.1 Bekman High-performance Liquid Chromatography (HPLC) Company Information
7.9.2 Bekman High-performance Liquid Chromatography (HPLC) Product Portfolio
7.9.3 Bekman High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.9.4 Bekman Main Business and Markets Served
7.9.5 Bekman Recent Developments/Updates
7.10 YoungLin
7.10.1 YoungLin High-performance Liquid Chromatography (HPLC) Company Information
7.10.2 YoungLin High-performance Liquid Chromatography (HPLC) Product Portfolio
7.10.3 YoungLin High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.10.4 YoungLin Main Business and Markets Served
7.10.5 YoungLin Recent Developments/Updates
7.11 GBC
7.11.1 GBC High-performance Liquid Chromatography (HPLC) Company Information
7.11.2 GBC High-performance Liquid Chromatography (HPLC) Product Portfolio
7.11.3 GBC High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.11.4 GBC Main Business and Markets Served
7.11.5 GBC Recent Developments/Updates
7.12 Gilson
7.12.1 Gilson High-performance Liquid Chromatography (HPLC) Company Information
7.12.2 Gilson High-performance Liquid Chromatography (HPLC) Product Portfolio
7.12.3 Gilson High-performance Liquid Chromatography (HPLC) Production, Value, Price and Gross Margin (2020-2025)
7.12.4 Gilson Main Business and Markets Served
7.12.5 Gilson Recent Developments/Updates
8 Industry Chain and Sales Channels Analysis
8.1 High-performance Liquid Chromatography (HPLC) Industry Chain Analysis
8.2 High-performance Liquid Chromatography (HPLC) Raw Material Supply Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.3 High-performance Liquid Chromatography (HPLC) Production Mode & Process Analysis
8.4 High-performance Liquid Chromatography (HPLC) Sales and Marketing
8.4.1 High-performance Liquid Chromatography (HPLC) Sales Channels
8.4.2 High-performance Liquid Chromatography (HPLC) Distributors
8.5 High-performance Liquid Chromatography (HPLC) Customer Analysis
9 High-performance Liquid Chromatography (HPLC) Market Dynamics
9.1 High-performance Liquid Chromatography (HPLC) Industry Trends
9.2 High-performance Liquid Chromatography (HPLC) Market Drivers
9.3 High-performance Liquid Chromatography (HPLC) Market Challenges
9.4 High-performance Liquid Chromatography (HPLC) Market Restraints
10 Research Findings and Conclusion
11 Methodology and Data Source
11.1 Methodology/Research Approach
11.1.1 Research Programs/Design
11.1.2 Market Size Estimation
11.1.3 Market Breakdown and Data Triangulation
11.2 Data Source
11.2.1 Secondary Sources
11.2.2 Primary Sources
11.3 Author List
11.4 Disclaimer
Agilent
Waters
Shimadzu
Thermo Fisher
PerkinElmer
Hitachi
Jasco
Knauer
Bekman
YoungLin
GBC
Gilson
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*If Applicable.