

Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described in 1990s. INO therapy was effective to improve oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN). Owing to its selective pulmonary vasodilator effects, iNO therapy is an important treatment for term newborns with hypoxemic respiratory failure due to PPHN. The Food and Drug Administration of the United States of America first approved iNO in 1999 for use as a medical gas to treat hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in term and late preterm neonates. Thereafter, iNO therapy is clinically applied to treat PPHN in term and late preterm neonates without consensus.
Market Analysis and Insights: Global Inhaled Nitric Oxide Market
Due to the COVID-19 pandemic, the global Inhaled Nitric Oxide market size is estimated to be worth US$ 1084 million in 2022 and is forecast to a readjusted size of US$ 1906.6 million by 2029 with a CAGR of 8.3% during the forecast period 2023-2029. Fully considering the economic change by this health crisis, 800 ppm accounting for % of the Inhaled Nitric Oxide global market in 2022, is projected to value US$ million by 2029, growing at a revised % CAGR from 2023 to 2029. While Near-term and Pre-term Infants PPHN segment is altered to an % CAGR throughout this forecast period.
Mallinckrodt monopolizes the global Inhaled Nitric Oxide market, holding a share about 65%.
North America is the largest market, with a share about 77%, followed by Asia-Pacific and Europe, have a share about 20 percent.
In terms of product, 800 ppm is the largest segment, with a share over 50%. And in terms of application, the largest application is Near-term and Pre-term Infants PPHN, followed by Children and Adult ARDS, etc.
Global Inhaled Nitric Oxide Scope and Market Size
The global Inhaled Nitric Oxide market is segmented by company, region (country), type and application. Players, stakeholders, and other participants in the global Inhaled Nitric Oxide market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region (country), type and application for the period 2018-2029.
Segment by Type
800 ppm
100 ppm
Others
Segment by Application
Near-term and Pre-term Infants PPHN
Children and Adult ARDS
Other Diseases
By Region
United States
Europe
China
Japan
Southeast Asia
India
Other Regions
By Company
Mallinckrodt
Praxair (Linde plc)
Air Liquide
BOC Healthcare (Linde Group)
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1 Inhaled Nitric Oxide Market Overview
1.1 Inhaled Nitric Oxide Product Scope
1.2 Inhaled Nitric Oxide Segment by Type
1.2.1 Global Inhaled Nitric Oxide Sales by Type (2018 & 2022 & 2029)
1.2.2 800 ppm
1.2.3 100 ppm
1.2.4 Others
1.3 Inhaled Nitric Oxide Segment by Application
1.3.1 Global Inhaled Nitric Oxide Sales Comparison by Application (2018 & 2022 & 2029)
1.3.2 Near-term and Pre-term Infants PPHN
1.3.3 Children and Adult ARDS
1.3.4 Other Diseases
1.4 Inhaled Nitric Oxide Market Estimates and Forecasts (2018-2029)
1.4.1 Global Inhaled Nitric Oxide Market Size in Value Growth Rate (2018-2029)
1.4.2 Global Inhaled Nitric Oxide Market Size in Volume Growth Rate (2018-2029)
1.4.3 Global Inhaled Nitric Oxide Price Trends (2018-2029)
2 Inhaled Nitric Oxide Estimates and Forecasts by Region
2.1 Global Inhaled Nitric Oxide Market Size by Region: 2018 VS 2022 VS 2029
2.2 Global Inhaled Nitric Oxide Retrospective Market Scenario by Region (2018-2023)
2.2.1 Global Inhaled Nitric Oxide Sales Market Share by Region (2018-2023)
2.2.2 Global Inhaled Nitric Oxide Revenue Market Share by Region (2018-2023)
2.3 Global Inhaled Nitric Oxide Market Estimates and Forecasts by Region (2024-2029)
2.3.1 Global Inhaled Nitric Oxide Sales Estimates and Forecasts by Region (2024-2029)
2.3.2 Global Inhaled Nitric Oxide Revenue Forecast by Region (2024-2029)
2.4 Geographic Market Analysis: Market Facts & Figures
2.4.1 United States Inhaled Nitric Oxide Estimates and Projections (2018-2029)
2.4.2 Europe Inhaled Nitric Oxide Estimates and Projections (2018-2029)
2.4.3 China Inhaled Nitric Oxide Estimates and Projections (2018-2029)
2.4.4 Japan Inhaled Nitric Oxide Estimates and Projections (2018-2029)
2.4.5 Southeast Asia Inhaled Nitric Oxide Estimates and Projections (2018-2029)
2.4.6 India Inhaled Nitric Oxide Estimates and Projections (2018-2029)
3 Global Inhaled Nitric Oxide Competition Landscape by Players
3.1 Global Top Inhaled Nitric Oxide Players by Sales (2018-2023)
3.2 Global Top Inhaled Nitric Oxide Players by Revenue (2018-2023)
3.3 Global Inhaled Nitric Oxide Market Share by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Inhaled Nitric Oxide as of 2022)
3.4 Global Inhaled Nitric Oxide Average Price by Company (2018-2023)
3.5 Manufacturers Inhaled Nitric Oxide Manufacturing Sites, Area Served, Product Type
3.6 Manufacturers Mergers & Acquisitions, Expansion Plans
4 Global Inhaled Nitric Oxide Market Size by Type
4.1 Global Inhaled Nitric Oxide Historic Market Review by Type (2018-2023)
4.1.1 Global Inhaled Nitric Oxide Sales by Type (2018-2023)
4.1.2 Global Inhaled Nitric Oxide Revenue by Type (2018-2023)
4.1.3 Global Inhaled Nitric Oxide Price by Type (2018-2023)
4.2 Global Inhaled Nitric Oxide Market Estimates and Forecasts by Type (2024-2029)
4.2.1 Global Inhaled Nitric Oxide Sales Forecast by Type (2024-2029)
4.2.2 Global Inhaled Nitric Oxide Revenue Forecast by Type (2024-2029)
4.2.3 Global Inhaled Nitric Oxide Price Forecast by Type (2024-2029)
5 Global Inhaled Nitric Oxide Market Size by Application
5.1 Global Inhaled Nitric Oxide Historic Market Review by Application (2018-2023)
5.1.1 Global Inhaled Nitric Oxide Sales by Application (2018-2023)
5.1.2 Global Inhaled Nitric Oxide Revenue by Application (2018-2023)
5.1.3 Global Inhaled Nitric Oxide Price by Application (2018-2023)
5.2 Global Inhaled Nitric Oxide Market Estimates and Forecasts by Application (2024-2029)
5.2.1 Global Inhaled Nitric Oxide Sales Forecast by Application (2024-2029)
5.2.2 Global Inhaled Nitric Oxide Revenue Forecast by Application (2024-2029)
5.2.3 Global Inhaled Nitric Oxide Price Forecast by Application (2024-2029)
6 United States Inhaled Nitric Oxide Market Facts & Figures
6.1 United States Inhaled Nitric Oxide Sales by Company
6.1.1 United States Inhaled Nitric Oxide Sales by Company (2018-2023)
6.1.2 United States Inhaled Nitric Oxide Revenue by Company (2018-2023)
6.2 United States Inhaled Nitric Oxide Sales Breakdown by Type
6.2.1 United States Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
6.2.2 United States Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
6.3 United States Inhaled Nitric Oxide Sales Breakdown by Application
6.3.1 United States Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
6.3.2 United States Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
7 Europe Inhaled Nitric Oxide Market Facts & Figures
7.1 Europe Inhaled Nitric Oxide Sales by Company
7.1.1 Europe Inhaled Nitric Oxide Sales by Company (2018-2023)
7.1.2 Europe Inhaled Nitric Oxide Revenue by Company (2018-2023)
7.2 Europe Inhaled Nitric Oxide Sales Breakdown by Type
7.2.1 Europe Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
7.2.2 Europe Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
7.3 Europe Inhaled Nitric Oxide Sales Breakdown by Application
7.3.1 Europe Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
7.3.2 Europe Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
8 China Inhaled Nitric Oxide Market Facts & Figures
8.1 China Inhaled Nitric Oxide Sales by Company
8.1.1 China Inhaled Nitric Oxide Sales by Company (2018-2023)
8.1.2 China Inhaled Nitric Oxide Revenue by Company (2018-2023)
8.2 China Inhaled Nitric Oxide Sales Breakdown by Type
8.2.1 China Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
8.2.2 China Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
8.3 China Inhaled Nitric Oxide Sales Breakdown by Application
8.3.1 China Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
8.3.2 China Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
9 Japan Inhaled Nitric Oxide Market Facts & Figures
9.1 Japan Inhaled Nitric Oxide Sales by Company
9.1.1 Japan Inhaled Nitric Oxide Sales by Company (2018-2023)
9.1.2 Japan Inhaled Nitric Oxide Revenue by Company (2018-2023)
9.2 Japan Inhaled Nitric Oxide Sales Breakdown by Type
9.2.1 Japan Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
9.2.2 Japan Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
9.3 Japan Inhaled Nitric Oxide Sales Breakdown by Application
9.3.1 Japan Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
9.3.2 Japan Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
10 Southeast Asia Inhaled Nitric Oxide Market Facts & Figures
10.1 Southeast Asia Inhaled Nitric Oxide Sales by Company
10.1.1 Southeast Asia Inhaled Nitric Oxide Sales by Company (2018-2023)
10.1.2 Southeast Asia Inhaled Nitric Oxide Revenue by Company (2018-2023)
10.2 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Type
10.2.1 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
10.2.2 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
10.3 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Application
10.3.1 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
10.3.2 Southeast Asia Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
11 India Inhaled Nitric Oxide Market Facts & Figures
11.1 India Inhaled Nitric Oxide Sales by Company
11.1.1 India Inhaled Nitric Oxide Sales by Company (2018-2023)
11.1.2 India Inhaled Nitric Oxide Revenue by Company (2018-2023)
11.2 India Inhaled Nitric Oxide Sales Breakdown by Type
11.2.1 India Inhaled Nitric Oxide Sales Breakdown by Type (2018-2023)
11.2.2 India Inhaled Nitric Oxide Sales Breakdown by Type (2024-2029)
11.3 India Inhaled Nitric Oxide Sales Breakdown by Application
11.3.1 India Inhaled Nitric Oxide Sales Breakdown by Application (2018-2023)
11.3.2 India Inhaled Nitric Oxide Sales Breakdown by Application (2024-2029)
12 Company Profiles and Key Figures in Inhaled Nitric Oxide Business
12.1 Mallinckrodt
12.1.1 Mallinckrodt Corporation Information
12.1.2 Mallinckrodt Business Overview
12.1.3 Mallinckrodt Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
12.1.4 Mallinckrodt Inhaled Nitric Oxide Products Offered
12.1.5 Mallinckrodt Recent Development
12.2 Praxair (Linde plc)
12.2.1 Praxair (Linde plc) Corporation Information
12.2.2 Praxair (Linde plc) Business Overview
12.2.3 Praxair (Linde plc) Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
12.2.4 Praxair (Linde plc) Inhaled Nitric Oxide Products Offered
12.2.5 Praxair (Linde plc) Recent Development
12.3 Air Liquide
12.3.1 Air Liquide Corporation Information
12.3.2 Air Liquide Business Overview
12.3.3 Air Liquide Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
12.3.4 Air Liquide Inhaled Nitric Oxide Products Offered
12.3.5 Air Liquide Recent Development
12.4 BOC Healthcare (Linde Group)
12.4.1 BOC Healthcare (Linde Group) Corporation Information
12.4.2 BOC Healthcare (Linde Group) Business Overview
12.4.3 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Sales, Revenue and Gross Margin (2018-2023)
12.4.4 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Products Offered
12.4.5 BOC Healthcare (Linde Group) Recent Development
13 Inhaled Nitric Oxide Manufacturing Cost Analysis
13.1 Inhaled Nitric Oxide Key Raw Materials Analysis
13.1.1 Key Raw Materials
13.1.2 Key Raw Materials Price Trend
13.1.3 Key Suppliers of Raw Materials
13.2 Proportion of Manufacturing Cost Structure
13.3 Manufacturing Process Analysis of Inhaled Nitric Oxide
13.4 Inhaled Nitric Oxide Industrial Chain Analysis
14 Marketing Channel, Distributors and Customers
14.1 Marketing Channel
14.2 Inhaled Nitric Oxide Distributors List
14.3 Inhaled Nitric Oxide Customers
15 Market Dynamics
15.1 Inhaled Nitric Oxide Industry Trends
15.2 Inhaled Nitric Oxide Market Drivers
15.3 Inhaled Nitric Oxide Market Challenges
15.4 Inhaled Nitric Oxide Market Restraints
16 Research Findings and Conclusion
17 Appendix
17.1 Research Methodology
17.1.1 Methodology/Research Approach
17.1.2 Data Source
17.2 Author List
17.3 Disclaimer
Mallinckrodt
Praxair (Linde plc)
Air Liquide
BOC Healthcare (Linde Group)
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*If Applicable.