An Organ-On-Chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-On-Chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels.
The primary focus of Organ-On-Chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney).
In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.
Market Analysis and Insights: Global Organ On Chip Market
Due to the COVID-19 pandemic, the global Organ On Chip market size is estimated to be worth US$ 56 million in 2022 and is forecast to a readjusted size of US$ 601.6 million by 2029 with a CAGR of 39.9% during the forecast period 2023-2029. Fully considering the economic change by this health crisis, Brain-on-a-chip accounting for % of the Organ On Chip global market in 2022, is projected to value US$ million by 2029, growing at a revised % CAGR from 2023 to 2029. While Pharmaceutical & Biotechnology Companies segment is altered to an % CAGR throughout this forecast period.
Global organ on chip key players include Emulate, TissUse, Hesperos, CN Bio Innovations, Tara Biosystems, etc. Global top 5 manufacturers hold a share about 55%.
North America is the largest market, with a share about 40%, followed by Europe and Asia-Pacific, both have a share about 50 percent.
In terms of product, Liver-on-a-chip is the largest segment, with a share about 30%. And in terms of application, the largest application is pharmaceutical & biotechnology companies, followed by academic & research institutes.
Global Organ On Chip Scope and Market Size
The global Organ On Chip market is segmented by company, region (country), type and end user. Players, stakeholders, and other participants in the global Organ On Chip market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on sales, revenue and forecast by region (country), type and end user for the period 2018-2029.
Segment by Type
Brain-on-a-chip
Liver-on-a-chip
Kidney-on-a-chip
Lung-on-a-chip
Heart-on-a-chip
Intestine-on-a-chip
Vessel-on-a-chip
Other Organs
Segment by End User
Pharmaceutical & Biotechnology Companies
Academic & Research Institutes
Cosmetics Industry
Others
By Region
United States
Europe
China
Japan
Southeast Asia
India
Other Regions
By Company
Emulate
TissUse
Hesperos
CN Bio Innovations
Tara Biosystems
Draper Laboratory
Mimetas
Nortis
Micronit Microtechnologies B.V.
Kirkstall
Cherry Biotech SAS
Else Kooi Laboratory
Beijing Daxiang Biotech Co., Ltd
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1 Organ On Chip Market Overview
1.1 Organ On Chip Product Scope
1.2 Organ On Chip Segment by Type
1.2.1 Global Organ On Chip Sales by Type (2018 & 2022 & 2029)
1.2.2 Brain-on-a-chip
1.2.3 Liver-on-a-chip
1.2.4 Kidney-on-a-chip
1.2.5 Lung-on-a-chip
1.2.6 Heart-on-a-chip
1.2.7 Intestine-on-a-chip
1.2.8 Vessel-on-a-chip
1.2.9 Other Organs
1.3 Organ On Chip Segment by End User
1.3.1 Global Organ On Chip Sales Comparison by End User (2018 & 2022 & 2029)
1.3.2 Pharmaceutical & Biotechnology Companies
1.3.3 Academic & Research Institutes
1.3.4 Cosmetics Industry
1.3.5 Others
1.4 Organ On Chip Market Estimates and Forecasts (2018-2029)
1.4.1 Global Organ On Chip Market Size in Value Growth Rate (2018-2029)
1.4.2 Global Organ On Chip Market Size in Volume Growth Rate (2018-2029)
1.4.3 Global Organ On Chip Price Trends (2018-2029)
2 Organ On Chip Estimates and Forecasts by Region
2.1 Global Organ On Chip Market Size by Region: 2018 VS 2022 VS 2029
2.2 Global Organ On Chip Retrospective Market Scenario by Region (2018-2023)
2.2.1 Global Organ On Chip Sales Market Share by Region (2018-2023)
2.2.2 Global Organ On Chip Revenue Market Share by Region (2018-2023)
2.3 Global Organ On Chip Market Estimates and Forecasts by Region (2024-2029)
2.3.1 Global Organ On Chip Sales Estimates and Forecasts by Region (2024-2029)
2.3.2 Global Organ On Chip Revenue Forecast by Region (2024-2029)
2.4 Geographic Market Analysis: Market Facts & Figures
2.4.1 United States Organ On Chip Estimates and Projections (2018-2029)
2.4.2 Europe Organ On Chip Estimates and Projections (2018-2029)
2.4.3 China Organ On Chip Estimates and Projections (2018-2029)
2.4.4 Japan Organ On Chip Estimates and Projections (2018-2029)
2.4.5 Southeast Asia Organ On Chip Estimates and Projections (2018-2029)
2.4.6 India Organ On Chip Estimates and Projections (2018-2029)
3 Global Organ On Chip Competition Landscape by Players
3.1 Global Top Organ On Chip Players by Sales (2018-2023)
3.2 Global Top Organ On Chip Players by Revenue (2018-2023)
3.3 Global Organ On Chip Market Share by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Organ On Chip as of 2022)
3.4 Global Organ On Chip Average Price by Company (2018-2023)
3.5 Manufacturers Organ On Chip Manufacturing Sites, Area Served, Product Type
3.6 Manufacturers Mergers & Acquisitions, Expansion Plans
4 Global Organ On Chip Market Size by Type
4.1 Global Organ On Chip Historic Market Review by Type (2018-2023)
4.1.1 Global Organ On Chip Sales by Type (2018-2023)
4.1.2 Global Organ On Chip Revenue by Type (2018-2023)
4.1.3 Global Organ On Chip Price by Type (2018-2023)
4.2 Global Organ On Chip Market Estimates and Forecasts by Type (2024-2029)
4.2.1 Global Organ On Chip Sales Forecast by Type (2024-2029)
4.2.2 Global Organ On Chip Revenue Forecast by Type (2024-2029)
4.2.3 Global Organ On Chip Price Forecast by Type (2024-2029)
5 Global Organ On Chip Market Size by End User
5.1 Global Organ On Chip Historic Market Review by End User (2018-2023)
5.1.1 Global Organ On Chip Sales by End User (2018-2023)
5.1.2 Global Organ On Chip Revenue by End User (2018-2023)
5.1.3 Global Organ On Chip Price by End User (2018-2023)
5.2 Global Organ On Chip Market Estimates and Forecasts by End User (2024-2029)
5.2.1 Global Organ On Chip Sales Forecast by End User (2024-2029)
5.2.2 Global Organ On Chip Revenue Forecast by End User (2024-2029)
5.2.3 Global Organ On Chip Price Forecast by End User (2024-2029)
6 United States Organ On Chip Market Facts & Figures
6.1 United States Organ On Chip Sales by Company
6.1.1 United States Organ On Chip Sales by Company (2018-2023)
6.1.2 United States Organ On Chip Revenue by Company (2018-2023)
6.2 United States Organ On Chip Sales Breakdown by Type
6.2.1 United States Organ On Chip Sales Breakdown by Type (2018-2023)
6.2.2 United States Organ On Chip Sales Breakdown by Type (2024-2029)
6.3 United States Organ On Chip Sales Breakdown by End User
6.3.1 United States Organ On Chip Sales Breakdown by End User (2018-2023)
6.3.2 United States Organ On Chip Sales Breakdown by End User (2024-2029)
7 Europe Organ On Chip Market Facts & Figures
7.1 Europe Organ On Chip Sales by Company
7.1.1 Europe Organ On Chip Sales by Company (2018-2023)
7.1.2 Europe Organ On Chip Revenue by Company (2018-2023)
7.2 Europe Organ On Chip Sales Breakdown by Type
7.2.1 Europe Organ On Chip Sales Breakdown by Type (2018-2023)
7.2.2 Europe Organ On Chip Sales Breakdown by Type (2024-2029)
7.3 Europe Organ On Chip Sales Breakdown by End User
7.3.1 Europe Organ On Chip Sales Breakdown by End User (2018-2023)
7.3.2 Europe Organ On Chip Sales Breakdown by End User (2024-2029)
8 China Organ On Chip Market Facts & Figures
8.1 China Organ On Chip Sales by Company
8.1.1 China Organ On Chip Sales by Company (2018-2023)
8.1.2 China Organ On Chip Revenue by Company (2018-2023)
8.2 China Organ On Chip Sales Breakdown by Type
8.2.1 China Organ On Chip Sales Breakdown by Type (2018-2023)
8.2.2 China Organ On Chip Sales Breakdown by Type (2024-2029)
8.3 China Organ On Chip Sales Breakdown by End User
8.3.1 China Organ On Chip Sales Breakdown by End User (2018-2023)
8.3.2 China Organ On Chip Sales Breakdown by End User (2024-2029)
9 Japan Organ On Chip Market Facts & Figures
9.1 Japan Organ On Chip Sales by Company
9.1.1 Japan Organ On Chip Sales by Company (2018-2023)
9.1.2 Japan Organ On Chip Revenue by Company (2018-2023)
9.2 Japan Organ On Chip Sales Breakdown by Type
9.2.1 Japan Organ On Chip Sales Breakdown by Type (2018-2023)
9.2.2 Japan Organ On Chip Sales Breakdown by Type (2024-2029)
9.3 Japan Organ On Chip Sales Breakdown by End User
9.3.1 Japan Organ On Chip Sales Breakdown by End User (2018-2023)
9.3.2 Japan Organ On Chip Sales Breakdown by End User (2024-2029)
10 Southeast Asia Organ On Chip Market Facts & Figures
10.1 Southeast Asia Organ On Chip Sales by Company
10.1.1 Southeast Asia Organ On Chip Sales by Company (2018-2023)
10.1.2 Southeast Asia Organ On Chip Revenue by Company (2018-2023)
10.2 Southeast Asia Organ On Chip Sales Breakdown by Type
10.2.1 Southeast Asia Organ On Chip Sales Breakdown by Type (2018-2023)
10.2.2 Southeast Asia Organ On Chip Sales Breakdown by Type (2024-2029)
10.3 Southeast Asia Organ On Chip Sales Breakdown by End User
10.3.1 Southeast Asia Organ On Chip Sales Breakdown by End User (2018-2023)
10.3.2 Southeast Asia Organ On Chip Sales Breakdown by End User (2024-2029)
11 India Organ On Chip Market Facts & Figures
11.1 India Organ On Chip Sales by Company
11.1.1 India Organ On Chip Sales by Company (2018-2023)
11.1.2 India Organ On Chip Revenue by Company (2018-2023)
11.2 India Organ On Chip Sales Breakdown by Type
11.2.1 India Organ On Chip Sales Breakdown by Type (2018-2023)
11.2.2 India Organ On Chip Sales Breakdown by Type (2024-2029)
11.3 India Organ On Chip Sales Breakdown by End User
11.3.1 India Organ On Chip Sales Breakdown by End User (2018-2023)
11.3.2 India Organ On Chip Sales Breakdown by End User (2024-2029)
12 Company Profiles and Key Figures in Organ On Chip Business
12.1 Emulate
12.1.1 Emulate Corporation Information
12.1.2 Emulate Business Overview
12.1.3 Emulate Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.1.4 Emulate Organ On Chip Products Offered
12.1.5 Emulate Recent Development
12.2 TissUse
12.2.1 TissUse Corporation Information
12.2.2 TissUse Business Overview
12.2.3 TissUse Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.2.4 TissUse Organ On Chip Products Offered
12.2.5 TissUse Recent Development
12.3 Hesperos
12.3.1 Hesperos Corporation Information
12.3.2 Hesperos Business Overview
12.3.3 Hesperos Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.3.4 Hesperos Organ On Chip Products Offered
12.3.5 Hesperos Recent Development
12.4 CN Bio Innovations
12.4.1 CN Bio Innovations Corporation Information
12.4.2 CN Bio Innovations Business Overview
12.4.3 CN Bio Innovations Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.4.4 CN Bio Innovations Organ On Chip Products Offered
12.4.5 CN Bio Innovations Recent Development
12.5 Tara Biosystems
12.5.1 Tara Biosystems Corporation Information
12.5.2 Tara Biosystems Business Overview
12.5.3 Tara Biosystems Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.5.4 Tara Biosystems Organ On Chip Products Offered
12.5.5 Tara Biosystems Recent Development
12.6 Draper Laboratory
12.6.1 Draper Laboratory Corporation Information
12.6.2 Draper Laboratory Business Overview
12.6.3 Draper Laboratory Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.6.4 Draper Laboratory Organ On Chip Products Offered
12.6.5 Draper Laboratory Recent Development
12.7 Mimetas
12.7.1 Mimetas Corporation Information
12.7.2 Mimetas Business Overview
12.7.3 Mimetas Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.7.4 Mimetas Organ On Chip Products Offered
12.7.5 Mimetas Recent Development
12.8 Nortis
12.8.1 Nortis Corporation Information
12.8.2 Nortis Business Overview
12.8.3 Nortis Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.8.4 Nortis Organ On Chip Products Offered
12.8.5 Nortis Recent Development
12.9 Micronit Microtechnologies B.V.
12.9.1 Micronit Microtechnologies B.V. Corporation Information
12.9.2 Micronit Microtechnologies B.V. Business Overview
12.9.3 Micronit Microtechnologies B.V. Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.9.4 Micronit Microtechnologies B.V. Organ On Chip Products Offered
12.9.5 Micronit Microtechnologies B.V. Recent Development
12.10 Kirkstall
12.10.1 Kirkstall Corporation Information
12.10.2 Kirkstall Business Overview
12.10.3 Kirkstall Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.10.4 Kirkstall Organ On Chip Products Offered
12.10.5 Kirkstall Recent Development
12.11 Cherry Biotech SAS
12.11.1 Cherry Biotech SAS Corporation Information
12.11.2 Cherry Biotech SAS Business Overview
12.11.3 Cherry Biotech SAS Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.11.4 Cherry Biotech SAS Organ On Chip Products Offered
12.11.5 Cherry Biotech SAS Recent Development
12.12 Else Kooi Laboratory
12.12.1 Else Kooi Laboratory Corporation Information
12.12.2 Else Kooi Laboratory Business Overview
12.12.3 Else Kooi Laboratory Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.12.4 Else Kooi Laboratory Organ On Chip Products Offered
12.12.5 Else Kooi Laboratory Recent Development
12.13 Beijing Daxiang Biotech Co., Ltd
12.13.1 Beijing Daxiang Biotech Co., Ltd Corporation Information
12.13.2 Beijing Daxiang Biotech Co., Ltd Business Overview
12.13.3 Beijing Daxiang Biotech Co., Ltd Organ On Chip Sales, Revenue and Gross Margin (2018-2023)
12.13.4 Beijing Daxiang Biotech Co., Ltd Organ On Chip Products Offered
12.13.5 Beijing Daxiang Biotech Co., Ltd Recent Development
13 Organ On Chip Manufacturing Cost Analysis
13.1 Organ On Chip Key Raw Materials Analysis
13.1.1 Key Raw Materials
13.1.2 Key Raw Materials Price Trend
13.1.3 Key Suppliers of Raw Materials
13.2 Proportion of Manufacturing Cost Structure
13.3 Manufacturing Process Analysis of Organ On Chip
13.4 Organ On Chip Industrial Chain Analysis
14 Marketing Channel, Distributors and Customers
14.1 Marketing Channel
14.2 Organ On Chip Distributors List
14.3 Organ On Chip Customers
15 Market Dynamics
15.1 Organ On Chip Industry Trends
15.2 Organ On Chip Market Drivers
15.3 Organ On Chip Market Challenges
15.4 Organ On Chip Market Restraints
16 Research Findings and Conclusion
17 Appendix
17.1 Research Methodology
17.1.1 Methodology/Research Approach
17.1.2 Data Source
17.2 Author List
17.3 Disclaimer
Emulate
TissUse
Hesperos
CN Bio Innovations
Tara Biosystems
Draper Laboratory
Mimetas
Nortis
Micronit Microtechnologies B.V.
Kirkstall
Cherry Biotech SAS
Else Kooi Laboratory
Beijing Daxiang Biotech Co., Ltd
听
听
*If Applicable.
