
Rolling circle amplification (RCA) is an isothermal enzymatic process that uses a circular DNA template and special DNA or RNA polymerases to amplify a short DNA or RNA primer to form a long single stranded DNA or RNA. The RCA product is a concatemer composed of tens to hundreds of tandem repeats that complement the circular template. The DNA amplification technique's power, simplicity, and versatility have made it an appealing tool for biomedical research and nanobiotechnology. RCA has traditionally been used to create sensitive diagnostic methods for a wide range of targets such as nucleic acids (DNA, RNA), small molecules, proteins, and cells. RCA has also received a great deal of attention in the fields of nanotechnology and nanobiotechnology.
The global Rolling Circle Amplification market was valued at US$ 835 million in 2023 and is anticipated to reach US$ 1647.7 million by 2030, witnessing a CAGR of 10.2% during the forecast period 2024-2030.
Immuno-RCA uses antibodies conjugated to oligonucleotides to detect individual proteins. A circular DNA template can be hybridized to it and then amplified by the enzyme phi29 polymerase using antibody-conjugated oligonucleotides as primers. This will result in the formation of RCP covalently linked to the antibody. Two antibodies are conjugated to two different oligonucleotides in PLA (proximity probes). Proximity probes are assumed to bind to their very close targets. In this case, they will serve as hybridization/ligation templates for two other oligonucleotides, resulting in a circular DNA template that can be amplified using one of the proximity probes as an RCA primer. The increasing application of rolling circle amplification has resulted in high growth of the rolling circle amplification market.
This report aims to provide a comprehensive presentation of the global market for Rolling Circle Amplification, with both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Rolling Circle Amplification.
Report Scope
The Rolling Circle Amplification market size, estimations, and forecasts are provided in terms of sales volume (K Units) and revenue ($ millions), considering 2023 as the base year, with history and forecast data for the period from 2019 to 2030. This report segments the global Rolling Circle Amplification market comprehensively. Regional market sizes, concerning products by Type, by Application, and by players, are also provided.
For a more in-depth understanding of the market, the report provides profiles of the competitive landscape, key competitors, and their respective market ranks. The report also discusses technological trends and new product developments.
The report will help the Rolling Circle Amplification manufacturers, new entrants, and industry chain related companies in this market with information on the revenues, sales volume, and average price for the overall market and the sub-segments across the different segments, by company, by Type, by Application, and by regions.
Market Segmentation
By Company
Thermo Fisher Scientific Inc
Abbott
QIAGEN
Agilent Technologies Inc
Bayer AG
BD
F. Hoffmann-La Roche Ltd
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Bio-Rad Laboratories Inc
Takara Bio, Inc
Segment by Type
Enzyme Assisted RCA Biosensor
Aunp RCA Biosensor
Aptamer Biosensors
Small Molecule Biosensors
Transcription Factor Biosensors
Mirna Biosensors
Protein Biosensors
Segment by Application
Disease Diagnosis
Biosensing
Drug Discovery
Nanotechnology
Other
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Southeast Asia
Latin America
Mexico
Brazil
Argentina
Middle East & Africa
Turkey
Saudi Arabia
UAE
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by region, by Type, by Application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Detailed analysis of Rolling Circle Amplification manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Sales, revenue of Rolling Circle Amplification in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 4: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 5: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 8: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 9: The main points and conclusions of the report.
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1 Rolling Circle Amplification Market Overview
1.1 Product Overview and Scope of Rolling Circle Amplification
1.2 Rolling Circle Amplification Segment by Type
1.2.1 Global Rolling Circle Amplification Market Value Comparison by Type (2024-2030)
1.2.2 Enzyme Assisted RCA Biosensor
1.2.3 Aunp RCA Biosensor
1.2.4 Aptamer Biosensors
1.2.5 Small Molecule Biosensors
1.2.6 Transcription Factor Biosensors
1.2.7 Mirna Biosensors
1.2.8 Protein Biosensors
1.3 Rolling Circle Amplification Segment by Application
1.3.1 Global Rolling Circle Amplification Market Value by Application: (2024-2030)
1.3.2 Disease Diagnosis
1.3.3 Biosensing
1.3.4 Drug Discovery
1.3.5 Nanotechnology
1.3.6 Other
1.4 Global Rolling Circle Amplification Market Size Estimates and Forecasts
1.4.1 Global Rolling Circle Amplification Revenue 2019-2030
1.4.2 Global Rolling Circle Amplification Sales 2019-2030
1.4.3 Global Rolling Circle Amplification Market Average Price (2019-2030)
1.5 Assumptions and Limitations
2 Rolling Circle Amplification Market Competition by Manufacturers
2.1 Global Rolling Circle Amplification Sales Market Share by Manufacturers (2019-2024)
2.2 Global Rolling Circle Amplification Revenue Market Share by Manufacturers (2019-2024)
2.3 Global Rolling Circle Amplification Average Price by Manufacturers (2019-2024)
2.4 Global Rolling Circle Amplification Industry Ranking 2022 VS 2023 VS 2024
2.5 Global Key Manufacturers of Rolling Circle Amplification, Manufacturing Sites & Headquarters
2.6 Global Key Manufacturers of Rolling Circle Amplification, Product Type & Application
2.7 Rolling Circle Amplification Market Competitive Situation and Trends
2.7.1 Rolling Circle Amplification Market Concentration Rate
2.7.2 The Global Top 5 and Top 10 Largest Rolling Circle Amplification Players Market Share by Revenue
2.7.3 Global Rolling Circle Amplification Market Share by Company Type (Tier 1, Tier 2 and Tier 3)
2.8 Manufacturers Mergers & Acquisitions, Expansion Plans
3 Rolling Circle Amplification Retrospective Market Scenario by Region
3.1 Global Rolling Circle Amplification Market Size by Region: 2019 Versus 2023 Versus 2030
3.2 Global Rolling Circle Amplification Global Rolling Circle Amplification Sales by Region: 2019-2030
3.2.1 Global Rolling Circle Amplification Sales by Region: 2019-2024
3.2.2 Global Rolling Circle Amplification Sales by Region: 2025-2030
3.3 Global Rolling Circle Amplification Global Rolling Circle Amplification Revenue by Region: 2019-2030
3.3.1 Global Rolling Circle Amplification Revenue by Region: 2019-2024
3.3.2 Global Rolling Circle Amplification Revenue by Region: 2025-2030
3.4 North America Rolling Circle Amplification Market Facts & Figures by Country
3.4.1 North America Rolling Circle Amplification Market Size by Country: 2019 VS 2023 VS 2030
3.4.2 North America Rolling Circle Amplification Sales by Country (2019-2030)
3.4.3 North America Rolling Circle Amplification Revenue by Country (2019-2030)
3.4.4 United States
3.4.5 Canada
3.5 Europe Rolling Circle Amplification Market Facts & Figures by Country
3.5.1 Europe Rolling Circle Amplification Market Size by Country: 2019 VS 2023 VS 2030
3.5.2 Europe Rolling Circle Amplification Sales by Country (2019-2030)
3.5.3 Europe Rolling Circle Amplification Revenue by Country (2019-2030)
3.5.4 Germany
3.5.5 France
3.5.6 U.K.
3.5.7 Italy
3.5.8 Russia
3.6 Asia Pacific Rolling Circle Amplification Market Facts & Figures by Country
3.6.1 Asia Pacific Rolling Circle Amplification Market Size by Country: 2019 VS 2023 VS 2030
3.6.2 Asia Pacific Rolling Circle Amplification Sales by Country (2019-2030)
3.6.3 Asia Pacific Rolling Circle Amplification Revenue by Country (2019-2030)
3.6.4 China
3.6.5 Japan
3.6.6 South Korea
3.6.7 India
3.6.8 Australia
3.6.9 China Taiwan
3.6.10 Southeast Asia
3.7 Latin America Rolling Circle Amplification Market Facts & Figures by Country
3.7.1 Latin America Rolling Circle Amplification Market Size by Country: 2019 VS 2023 VS 2030
3.7.2 Latin America Rolling Circle Amplification Sales by Country (2019-2030)
3.7.3 Latin America Rolling Circle Amplification Revenue by Country (2019-2030)
3.7.4 Mexico
3.7.5 Brazil
3.7.6 Argentina
3.8 Middle East and Africa Rolling Circle Amplification Market Facts & Figures by Country
3.8.1 Middle East and Africa Rolling Circle Amplification Market Size by Country: 2019 VS 2023 VS 2030
3.8.2 Middle East and Africa Rolling Circle Amplification Sales by Country (2019-2030)
3.8.3 Middle East and Africa Rolling Circle Amplification Revenue by Country (2019-2030)
3.8.4 Turkey
3.8.5 Saudi Arabia
3.8.6 UAE
4 Segment by Type
4.1 Global Rolling Circle Amplification Sales by Type (2019-2030)
4.1.1 Global Rolling Circle Amplification Sales by Type (2019-2024)
4.1.2 Global Rolling Circle Amplification Sales by Type (2025-2030)
4.1.3 Global Rolling Circle Amplification Sales Market Share by Type (2019-2030)
4.2 Global Rolling Circle Amplification Revenue by Type (2019-2030)
4.2.1 Global Rolling Circle Amplification Revenue by Type (2019-2024)
4.2.2 Global Rolling Circle Amplification Revenue by Type (2025-2030)
4.2.3 Global Rolling Circle Amplification Revenue Market Share by Type (2019-2030)
4.3 Global Rolling Circle Amplification Price by Type (2019-2030)
5 Segment by Application
5.1 Global Rolling Circle Amplification Sales by Application (2019-2030)
5.1.1 Global Rolling Circle Amplification Sales by Application (2019-2024)
5.1.2 Global Rolling Circle Amplification Sales by Application (2025-2030)
5.1.3 Global Rolling Circle Amplification Sales Market Share by Application (2019-2030)
5.2 Global Rolling Circle Amplification Revenue by Application (2019-2030)
5.2.1 Global Rolling Circle Amplification Revenue by Application (2019-2024)
5.2.2 Global Rolling Circle Amplification Revenue by Application (2025-2030)
5.2.3 Global Rolling Circle Amplification Revenue Market Share by Application (2019-2030)
5.3 Global Rolling Circle Amplification Price by Application (2019-2030)
6 Key Companies Profiled
6.1 Thermo Fisher Scientific Inc
6.1.1 Thermo Fisher Scientific Inc Corporation Information
6.1.2 Thermo Fisher Scientific Inc Description and Business Overview
6.1.3 Thermo Fisher Scientific Inc Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.1.4 Thermo Fisher Scientific Inc Rolling Circle Amplification Product Portfolio
6.1.5 Thermo Fisher Scientific Inc Recent Developments/Updates
6.2 Abbott
6.2.1 Abbott Corporation Information
6.2.2 Abbott Description and Business Overview
6.2.3 Abbott Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.2.4 Abbott Rolling Circle Amplification Product Portfolio
6.2.5 Abbott Recent Developments/Updates
6.3 QIAGEN
6.3.1 QIAGEN Corporation Information
6.3.2 QIAGEN Description and Business Overview
6.3.3 QIAGEN Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.3.4 QIAGEN Rolling Circle Amplification Product Portfolio
6.3.5 QIAGEN Recent Developments/Updates
6.4 Agilent Technologies Inc
6.4.1 Agilent Technologies Inc Corporation Information
6.4.2 Agilent Technologies Inc Description and Business Overview
6.4.3 Agilent Technologies Inc Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.4.4 Agilent Technologies Inc Rolling Circle Amplification Product Portfolio
6.4.5 Agilent Technologies Inc Recent Developments/Updates
6.5 Bayer AG
6.5.1 Bayer AG Corporation Information
6.5.2 Bayer AG Description and Business Overview
6.5.3 Bayer AG Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.5.4 Bayer AG Rolling Circle Amplification Product Portfolio
6.5.5 Bayer AG Recent Developments/Updates
6.6 BD
6.6.1 BD Corporation Information
6.6.2 BD Description and Business Overview
6.6.3 BD Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.6.4 BD Rolling Circle Amplification Product Portfolio
6.6.5 BD Recent Developments/Updates
6.7 F. Hoffmann-La Roche Ltd
6.6.1 F. Hoffmann-La Roche Ltd Corporation Information
6.6.2 F. Hoffmann-La Roche Ltd Description and Business Overview
6.6.3 F. Hoffmann-La Roche Ltd Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.4.4 F. Hoffmann-La Roche Ltd Rolling Circle Amplification Product Portfolio
6.7.5 F. Hoffmann-La Roche Ltd Recent Developments/Updates
6.8 µþ±õ°¿²Ñɸé±õ·¡±«³Ý
6.8.1 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Corporation Information
6.8.2 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Description and Business Overview
6.8.3 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.8.4 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Rolling Circle Amplification Product Portfolio
6.8.5 µþ±õ°¿²Ñɸé±õ·¡±«³Ý Recent Developments/Updates
6.9 Bio-Rad Laboratories Inc
6.9.1 Bio-Rad Laboratories Inc Corporation Information
6.9.2 Bio-Rad Laboratories Inc Description and Business Overview
6.9.3 Bio-Rad Laboratories Inc Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.9.4 Bio-Rad Laboratories Inc Rolling Circle Amplification Product Portfolio
6.9.5 Bio-Rad Laboratories Inc Recent Developments/Updates
6.10 Takara Bio, Inc
6.10.1 Takara Bio, Inc Corporation Information
6.10.2 Takara Bio, Inc Description and Business Overview
6.10.3 Takara Bio, Inc Rolling Circle Amplification Sales, Revenue and Gross Margin (2019-2024)
6.10.4 Takara Bio, Inc Rolling Circle Amplification Product Portfolio
6.10.5 Takara Bio, Inc Recent Developments/Updates
7 Industry Chain and Sales Channels Analysis
7.1 Rolling Circle Amplification Industry Chain Analysis
7.2 Rolling Circle Amplification Key Raw Materials
7.2.1 Key Raw Materials
7.2.2 Raw Materials Key Suppliers
7.3 Rolling Circle Amplification Production Mode & Process
7.4 Rolling Circle Amplification Sales and Marketing
7.4.1 Rolling Circle Amplification Sales Channels
7.4.2 Rolling Circle Amplification Distributors
7.5 Rolling Circle Amplification Customers
8 Rolling Circle Amplification Market Dynamics
8.1 Rolling Circle Amplification Industry Trends
8.2 Rolling Circle Amplification Market Drivers
8.3 Rolling Circle Amplification Market Challenges
8.4 Rolling Circle Amplification Market Restraints
9 Research Finding and Conclusion
10 Methodology and Data Source
10.1 Methodology/Research Approach
10.1.1 Research Programs/Design
10.1.2 Market Size Estimation
10.1.3 Market Breakdown and Data Triangulation
10.2 Data Source
10.2.1 Secondary Sources
10.2.2 Primary Sources
10.3 Author List
10.4 Disclaimer
Thermo Fisher Scientific Inc
Abbott
QIAGEN
Agilent Technologies Inc
Bayer AG
BD
F. Hoffmann-La Roche Ltd
µþ±õ°¿²Ñɸé±õ·¡±«³Ý
Bio-Rad Laboratories Inc
Takara Bio, Inc
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